Synthesis, characterization and microbiological activity of a Zn(II) complex of a novel benzofurazan derivative

被引：0
|
作者：
Grabchev, I. [1 ]
Gajda, T. [2 ]
Yordanova, S. [3 ]
Purak, S. [2 ]
Vasileva-Tonkova, E. [4 ]
Stoyanov, S. [3 ]
机构：
[1] Sofia Univ St Kliment Ohridski, Fac Med, Sofia 1407, Bulgaria
[2] Univ Szeged, Dept Inorgan & Analyt Chem, Dom Ter 7, H-6720 Szeged, Hungary
[3] Sofia Univ St Kliment Ohridski, Fac Chem & Pharm, Sofia 1164, Bulgaria
[4] Bulgarian Acad Sci, Inst Microbiol & Crystallog, BU-1113 Sofia, Bulgaria
来源：
BULGARIAN CHEMICAL COMMUNICATIONS | 2017年 / 49卷
关键词：
metal complexes; cyclam; benzofurazane; microbiological; NMR; CYCLAM; ANTIBACTERIAL; CU(II);
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Complex formation of Zn(II) and Al(III) ions with a novel 4-nitro-benzofurazan-cyclam conjugate has been investigated by H-1-NMR and electronic (UV-vis and fluorescence) spectroscopy in dimethylsulfoxide. A stable Zn(II) complex [Zn(P1)(NO3)(2)] has been isolated, characterised, and in vitro its antimicrobial activity was tested. Good antibacterial activity against several Gram-positive and Gram-negative bacteria and antifungal activity against two yeasts has been observed.
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收藏
页码：76 / 82
页数：7
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