Synthesis, characterization and microbiological activity of a Zn(II) complex of a novel benzofurazan derivative

被引：0

作者：

Grabchev, I. ^{[1
]}

Gajda, T. ^{[2
]}

Yordanova, S. ^{[3
]}

Purak, S. ^{[2
]}

Vasileva-Tonkova, E. ^{[4
]}

Stoyanov, S. ^{[3
]}

机构：

[1] Sofia Univ St Kliment Ohridski, Fac Med, Sofia 1407, Bulgaria

[2] Univ Szeged, Dept Inorgan & Analyt Chem, Dom Ter 7, H-6720 Szeged, Hungary

[3] Sofia Univ St Kliment Ohridski, Fac Chem & Pharm, Sofia 1164, Bulgaria

[4] Bulgarian Acad Sci, Inst Microbiol & Crystallog, BU-1113 Sofia, Bulgaria

来源：

BULGARIAN CHEMICAL COMMUNICATIONS | 2017年 / 49卷

关键词：

metal complexes; cyclam; benzofurazane; microbiological; NMR; CYCLAM; ANTIBACTERIAL; CU(II);

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Complex formation of Zn(II) and Al(III) ions with a novel 4-nitro-benzofurazan-cyclam conjugate has been investigated by H-1-NMR and electronic (UV-vis and fluorescence) spectroscopy in dimethylsulfoxide. A stable Zn(II) complex [Zn(P1)(NO3)(2)] has been isolated, characterised, and in vitro its antimicrobial activity was tested. Good antibacterial activity against several Gram-positive and Gram-negative bacteria and antifungal activity against two yeasts has been observed.

引用

页码：76 / 82

页数：7

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