Update on HIV viral-load assays: new technologies and testing in resource-limited settings

被引:3
|
作者
de Mendoza, Carmen [1 ]
Soriano, Vincent [1 ]
机构
[1] Hosp Carlos III, Dept Infect Dis, Madrid 28029, Spain
关键词
dried blood spots; HIV; HIV-RNA; HIV subtypes; real-time PCR; viral load; NUCLISENS EASYQ HIV-1; COBAS TAQMAN HIV-1; DRIED BLOOD SPOTS; VIRUS TYPE-1 RNA; NON-B SUBTYPES; WHOLE-BLOOD; MULTICENTER EVALUATION; QUANTITATIVE DETECTION; FILTER-PAPER; PLASMA;
D O I
10.2217/FVL.09.24
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Assessment of viral load is one of the best predictors of clinical progression, as well as the main parameter to assess treatment response in HIV-positive patients. Reproducible and sensitive assays based on real-time PCR technology have been developed to quantify HIV in the bloodstream of infected persons, Recent improvements have allowed reliable measurements of viremia in non-B subtypes. Testing of samples other than serum or plasma has been challenging, but is particularly important for developing countries.
引用
收藏
页码:423 / 430
页数:8
相关论文
共 50 条
  • [21] HIV viral load monitoring in resource-limited regions: Optional or necessary?
    Calmy, Alexandra
    Ford, Nathan
    Hirschel, Bernard
    Reynolds, Steven J.
    Lynen, Lut
    Goemaere, Eric
    de la Vega, Felipe Garcia
    Perrin, Luc
    Rodriguez, William
    CLINICAL INFECTIOUS DISEASES, 2007, 44 (01) : 128 - 134
  • [22] Monitoring the Quality of HIV-1 Viral Load Testing through a Proficiency Testing Program Using Dried Tube Specimens in Resource-Limited Settings
    Nguyen, Shon
    Ramos, Artur
    Chang, Joy
    Li, Bin
    Shanmugam, Vedapuri
    Boeras, Debrah
    Nkengasong, John N.
    Yang, Chunfu
    Ellenberger, Dennis
    JOURNAL OF CLINICAL MICROBIOLOGY, 2015, 53 (04) : 1129 - 1136
  • [23] The Price of Nonabandonment: HIV in Resource-Limited Settings
    Khademi, Amin
    Saure, Denis R.
    Schaefer, Andrew J.
    Braithwaite, Ronald S.
    Roberts, Mark S.
    M&SOM-MANUFACTURING & SERVICE OPERATIONS MANAGEMENT, 2015, 17 (04) : 554 - 570
  • [24] Extending HIV care in resource-limited settings
    Wools-Kaloustian K.
    Kimaiyo S.
    Current HIV/AIDS Reports, 2006, 3 (4) : 182 - 186
  • [25] Molecular Oncology Testing in Resource-Limited Settings
    Gulley, Margaret L.
    Morgan, Douglas R.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2014, 16 (06): : 601 - 611
  • [26] Low-cost assays for monitoring HIV infected individuals in resource-limited settings
    Balakrishnan, Pachamuthu
    Iqbal, Hussain Syed
    Shanmugham, Saravanan
    Mohanakrishnan, Janardhanan
    Solomon, Sunil S.
    Mayer, Kenneth H.
    Solomon, Suniti
    INDIAN JOURNAL OF MEDICAL RESEARCH, 2011, 134 (06) : 823 - 834
  • [27] HIV Self-Testing in Resource-Limited Settings: Regulatory and Policy Considerations
    Vincent Wong
    Cheryl Johnson
    Elliot Cowan
    Matthew Rosenthal
    Rosanna Peeling
    Maria Miralles
    Anita Sands
    Charlene Brown
    AIDS and Behavior, 2014, 18 : 415 - 421
  • [28] HIV Self-Testing in Resource-Limited Settings: Regulatory and Policy Considerations
    Wong, Vincent
    Johnson, Cheryl
    Cowan, Elliot
    Rosenthal, Matthew
    Peeling, Rosanna
    Miralles, Maria
    Sands, Anita
    Brown, Charlene
    AIDS AND BEHAVIOR, 2014, 18 : S415 - S421
  • [29] WHO Releases New HIV Guidelines Aimed At Resource-Limited Settings
    Rivas, Pablo
    Ustero, Pilar
    AIDS REVIEWS, 2010, 12 (01) : 62 - 63
  • [30] Beyond first-line HIV treatment regimens: the current state of antiretroviral regimens, viral load monitoring, and resistance testing in resource-limited settings
    Kumarasamy, Nagalingeswaran
    Krishnan, Sheela
    CURRENT OPINION IN HIV AND AIDS, 2013, 8 (06) : 586 - 590