Update on HIV viral-load assays: new technologies and testing in resource-limited settings

被引:3
|
作者
de Mendoza, Carmen [1 ]
Soriano, Vincent [1 ]
机构
[1] Hosp Carlos III, Dept Infect Dis, Madrid 28029, Spain
关键词
dried blood spots; HIV; HIV-RNA; HIV subtypes; real-time PCR; viral load; NUCLISENS EASYQ HIV-1; COBAS TAQMAN HIV-1; DRIED BLOOD SPOTS; VIRUS TYPE-1 RNA; NON-B SUBTYPES; WHOLE-BLOOD; MULTICENTER EVALUATION; QUANTITATIVE DETECTION; FILTER-PAPER; PLASMA;
D O I
10.2217/FVL.09.24
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Assessment of viral load is one of the best predictors of clinical progression, as well as the main parameter to assess treatment response in HIV-positive patients. Reproducible and sensitive assays based on real-time PCR technology have been developed to quantify HIV in the bloodstream of infected persons, Recent improvements have allowed reliable measurements of viremia in non-B subtypes. Testing of samples other than serum or plasma has been challenging, but is particularly important for developing countries.
引用
收藏
页码:423 / 430
页数:8
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