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Update on HIV viral-load assays: new technologies and testing in resource-limited settings
被引:3
|作者:
de Mendoza, Carmen
[1
]
Soriano, Vincent
[1
]
机构:
[1] Hosp Carlos III, Dept Infect Dis, Madrid 28029, Spain
关键词:
dried blood spots;
HIV;
HIV-RNA;
HIV subtypes;
real-time PCR;
viral load;
NUCLISENS EASYQ HIV-1;
COBAS TAQMAN HIV-1;
DRIED BLOOD SPOTS;
VIRUS TYPE-1 RNA;
NON-B SUBTYPES;
WHOLE-BLOOD;
MULTICENTER EVALUATION;
QUANTITATIVE DETECTION;
FILTER-PAPER;
PLASMA;
D O I:
10.2217/FVL.09.24
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
Assessment of viral load is one of the best predictors of clinical progression, as well as the main parameter to assess treatment response in HIV-positive patients. Reproducible and sensitive assays based on real-time PCR technology have been developed to quantify HIV in the bloodstream of infected persons, Recent improvements have allowed reliable measurements of viremia in non-B subtypes. Testing of samples other than serum or plasma has been challenging, but is particularly important for developing countries.
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页码:423 / 430
页数:8
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