Coronavirus Disease 2019 Vaccine Development: An Overview

被引:16
|
作者
Sumirtanurdin, Riyadi [1 ,2 ]
Barliana, Melisa Intan [2 ,3 ]
机构
[1] Univ Padjadjaran, Fac Pharm, Educ, Bandung, Indonesia
[2] Univ Padjadjaran, Dept Biol Pharm, Biotechnol Pharm Lab, Fac Pharm, Bandung, Indonesia
[3] Univ Padjadjaran, Ctr Excellence Higher Educ Pharmaceut Care Innova, Bandung, Indonesia
关键词
SARS-CoV-2; challenges; platforms; progress; RECEPTOR-BINDING DOMAIN; DENDRITIC CELLS; VIRAL VECTORS; VIRUS; PARTICLES;
D O I
10.1089/vim.2020.0119
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To this day, the coronavirus disease 2019 (COVID-19) pandemic has not shown signs of abating. Moreover, the virus responsible for the pandemic, severe acute respiratory syndrome coronavirus 2, has evolved into three different variants. This phenomenon highlights an even greater need to develop drugs and vaccines to control the rate of infection and spread of the disease. As of July 7, 2020, at least 160 vaccine candidates, 21 of which have entered the clinical trial phase, have been developed. This article describes the latest advances in development, reliable platforms, strategies used, and challenges that remain in developing COVID-19 vaccines.
引用
收藏
页码:134 / 144
页数:11
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