Placebo surgery for Parkinson's disease: Do the benefits outweigh the risks?

被引:32
|
作者
Clark, PA [1 ]
机构
[1] St Josephs Univ, John McShane Chair Eth, Philadelphia, PA 19131 USA
来源
JOURNAL OF LAW MEDICINE & ETHICS | 2002年 / 30卷 / 01期
关键词
D O I
10.1111/j.1748-720X.2002.tb00720.x
中图分类号
B82 [伦理学(道德学)];
学科分类号
摘要
Placebo-controlled clinical trials of fetal tissue transplants for Parkinson's disease patients involve subjecting those in the control group to sham neurosurgery. These patients receive four tiny burr holes, drilled through the wrinkle lines above the eyebrows into the skull. to clear a path-way to the brain, The author argues that this practice is unethical because it violates the principles of respect for persons, beneficence, and justice. The results from both animal and human studies have failed to show substantial enduring effects from these trials, the research design appears to be substantially flawed, and there art, viable options being offered that art, less harmful to human subjects. As a result, the author argues that placebo surgery, in controlled trials using fetal tissue for Parkinson's disease be stopped immediately.
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页码:58 / +
页数:67
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