Molecular markers and selection for complex traits in plants: Learning from the last 20 years

被引:527
|
作者
Bernardo, Rex [1 ]
机构
[1] Univ Minnesota, Dep Agron & Plant Genet, St Paul, MN 55108 USA
关键词
D O I
10.2135/cropsci2008.03.0131
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
In the mid-1980s, the development of abundant molecular markers, appropriate statistical procedures, and user-friendly computer software that implemented these statistical procedures permitted the detection of molecular markers associated with quantitative trait loci (QTL) for complex traits. Marker-assisted selection was then proposed as a means of exploiting markers linked to QTL to develop improved cultivars. But while thousands of marker-trait associations have been reported for many traits in different plant species, far fewer examples of successfully exploiting mapped QTL have been reported in the literature. Key lessons learned from applying markers in plant breeding include the following: (i) the purpose of detecting QTL should be clearly defined before embarking on QTL mapping; (ii) procedures for marker-based selection depend on the number of QTL; (iii) estimates of QTL effects for complex traits are often inconsistent; and (iv) gain per unit cost and time rather than gain per cycle should be considered. Future applications for complex traits will likely focus on predictive methodologies for marker-based selection before phenotyping and for marker-based selection without QTL mapping. These applications will take advantage of cheaper costs of genotyping than of phenotyping.
引用
收藏
页码:1649 / 1664
页数:16
相关论文
共 50 条
  • [41] Prediction of industrial tomato hybrids from agronomic traits and ISSR molecular markers
    Figueiredo, A. S. T.
    Resende, J. T. V.
    Faria, M. V.
    Da-Silva, P. R.
    Fagundes, B. S.
    Morales, R. G. F.
    GENETICS AND MOLECULAR RESEARCH, 2016, 15 (02)
  • [42] Alternative pathways leading to ascorbate biosynthesis in plants: lessons from the last 25 years
    Quinones, Cherryl O.
    Gesto-Borroto, Reinier
    Wilson, Rachael, V
    Hernandez-Madrigal, Sara, V
    Lorence, Argelia
    JOURNAL OF EXPERIMENTAL BOTANY, 2024, 75 (09) : 2644 - 2663
  • [43] NATURAL-SELECTION ASSOCIATED WITH BIRTH-WEIGHT .3. CHANGES OVER THE LAST 20 YEARS
    TERRENATO, L
    GRAVINA, MF
    MARTINI, AS
    ULIZZI, L
    ANNALS OF HUMAN GENETICS, 1981, 45 (JUL) : 267 - 278
  • [44] Molecular dissection of complex agronomic traits of rice:a team effort by Chinese scientists in recent years
    Jianru Zuo
    Jiayang Li
    National Science Review, 2014, 1 (02) : 253 - 276
  • [45] Molecular dissection of complex agronomic traits of rice: a team effort by Chinese scientists in recent years
    Zuo, Jianru
    Li, Jiayang
    NATIONAL SCIENCE REVIEW, 2014, 1 (02) : 253 - 276
  • [46] Heterogeneity of blastomycosis-like pyoderma: A selection of cases from the last 35 years
    Scuderi, Salvatore
    O'Brien, Blake
    Robertson, Ivan
    Weedon, David
    AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2017, 58 (02) : 139 - 141
  • [47] Revised estimates of mortality from burns in the last 20 years at the Birmingham Burns Centre
    Rashid, A
    Khanna, A
    Gowar, JP
    Bull, JP
    BURNS, 2001, 27 (07) : 723 - 730
  • [49] From racemates to single enantiomers - Chiral synthetic drugs over the last 20 years
    Murakami, Hisamichi
    NOVEL OPTICAL RESOLUTION TECHNOLOGIES, 2007, 269 : 273 - 299
  • [50] ENVIRONMENTAL SHIFTS IN THE LAST 20 000 YEARS - ISOTOPIC EVIDENCE FROM EQUUS CAVE
    LEETHORP, JA
    BEAUMONT, PB
    SOUTH AFRICAN JOURNAL OF SCIENCE, 1990, 86 (7-10) : 452 - 453