Prevalence of Cancer in Adults With Congenital Heart Disease Compared With the General Population

被引：42

作者：

Gurvitz, Michelle ^{[1
,2
]}

Ionescu-Ittu, Raluca ^{[3
]}

Guo, Liming ^{[3
]}

Eisenberg, Mark J. ^{[4
]}

Abrahamowicz, Michal ^{[5
]}

Pilote, Louise ^{[4
]}

Marelli, Ariane J. ^{[3
]}

机构：

[1] Childrens Hosp Boston, Dept Cardiol, Boston, MA 02115 USA

[2] Harvard Med Sch, Brigham & Womens Hosp, Div Cardiovasc, Boston, MA 02115 USA

[3] McGill Univ, McGill Adult Unit Congenital Heart Dis Excellence, Montreal, PQ, Canada

[4] McGill Univ, Jewish Gen Hosp, Div Cardiol, Montreal, PQ, Canada

[5] McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2016年 / 118卷 / 11期

关键词：

CARDIAC-CATHETERIZATION; IONIZING-RADIATION; NOONAN SYNDROME; EXPOSURE; CHILDREN; RISK; CHILDHOOD; COHORT; DAMAGE;

D O I：

10.1016/j.amjcard.2016.08.057

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prevalence rate of cancer among adult patients with congenital heart disease (CHD) in North America has not been previously described. The Quebec adult CHD database was used to determine the prevalence rate of cancer among adult patients with CHD measured as the number of adults with CHD and cancer alive in 2005 per 1,000 adults with CHD. This prevalence rate was compared with the prevalence rate of cancer in the general population of adults in Canada. Types of cancer among the CHD group were described by gender and age. Adult patients with CHD had a 1.6 to 2 times higher prevalence of cancer at 2, 5, and 10 years for both men and women. Overall, men had a greater prevalence of total cancers in all-time durations than did women. Breast, colon, and prostate cancer were the most common cancers reported in adults with CHD. In conclusion, we observed an increased prevalence of cancer among the adult CUD population of Quebec compared with the general Canadian population. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：1742 / 1750

页数：9

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