Unprecedented Construction of C=C Double Bonds via Ir-Catalyzed Dehydrogenative and Dehydrative Cross-Couplings

被引：35
|
作者：
Nie, Shao-zhen [1 ]
Sun, Xiang [1 ]
Wei, Wen-tao [1 ]
Zhang, Xue-jing [1 ]
Yan, Ming [1 ]
Xiao, Jian-liang [2 ]
机构：
[1] Sun Yat Sen Univ, Inst Drug Synth & Pharmaceut Proc, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China
[2] Univ Liverpool, Liverpool Ctr Mat & Catalysis, Dept Chem, Liverpool L69 7ZD, Merseyside, England
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 10期
基金：
中国国家自然科学基金;
关键词：
C-H ACTIVATION; BORROWING HYDROGEN; TERTIARY-AMINES; NITROGEN; HETEROCYCLES; ADJACENT; ATOM; CDC;
D O I：
10.1021/ol4008469
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Unprecedented constructions of C=C double bonds have been achieved by Ir-catalyzed intramolecular dehydrogenative and dehydrative cross-coupling of tertiary amines and ketones. The reactions are proposed to proceed via an Ir-mediated C-H activation mechanism.
引用
收藏
页码：2394 / 2397
页数：4
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