Unprecedented Construction of C=C Double Bonds via Ir-Catalyzed Dehydrogenative and Dehydrative Cross-Couplings

被引：35

作者：

Nie, Shao-zhen ^{[1
]}

Sun, Xiang ^{[1
]}

Wei, Wen-tao ^{[1
]}

Zhang, Xue-jing ^{[1
]}

Yan, Ming ^{[1
]}

Xiao, Jian-liang ^{[2
]}

机构：

[1] Sun Yat Sen Univ, Inst Drug Synth & Pharmaceut Proc, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China

[2] Univ Liverpool, Liverpool Ctr Mat & Catalysis, Dept Chem, Liverpool L69 7ZD, Merseyside, England

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 10期

基金：

中国国家自然科学基金;

关键词：

C-H ACTIVATION; BORROWING HYDROGEN; TERTIARY-AMINES; NITROGEN; HETEROCYCLES; ADJACENT; ATOM; CDC;

D O I：

10.1021/ol4008469

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Unprecedented constructions of C=C double bonds have been achieved by Ir-catalyzed intramolecular dehydrogenative and dehydrative cross-coupling of tertiary amines and ketones. The reactions are proposed to proceed via an Ir-mediated C-H activation mechanism.

引用

页码：2394 / 2397

页数：4

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