Efficient one-pot synthesis of α-aminophosphonates from aldehydes and ketones catalyzed by ytterbium(III) triflate

被引:20
|
作者
Heo, Yeon [1 ]
Cho, Dae Hyan [1 ]
Mishra, Mithilesh Kumar [1 ]
Jang, Doo Ok [1 ]
机构
[1] Yonsei Univ, Dept Chem, Wonju 220710, South Korea
关键词
Aldehyde; Ketone; alpha-Aminophosphonate; Ytterbium(III) triflate; LEWIS-ACID CATALYSTS; AMINO-PHOSPHONATES; RECYCLABLE CATALYST; FACILE SYNTHESIS; WATER; INHIBITORS; CHLORIDE; PHOSPHITE; ESTERS;
D O I
10.1016/j.tetlet.2012.05.068
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient three component one-pot synthesis of N-silylated alpha-aminophosphonates and alpha,alpha-disubstituted alpha-aminophosphonates was developed using Yb(OTf)(3) as a catalyst at room temperature under mild conditions. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3897 / 3899
页数:3
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