Evaluation of genotoxic effects of aqueous extract of Croton caudatus Geiseler leaves on mice

被引：0
|
作者：
Leishangthem, Surendrajit [1 ]
Thounaojam, Bhagirath [1 ]
机构：
[1] Manipur Univ, Dept Life Sci, Imphal 795003, Manipur, India
来源：
CARYOLOGIA | 2011年 / 64卷 / 04期
关键词：
Chromosome aberration; Clastogenic effect; Cytogenetic; Intraperitoneal; Synaptonemal complex; SYNAPTONEMAL COMPLEX DAMAGE; LECHLERI; SANGRE;
D O I：
暂无
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Croton caudatus Geiseler is widely used in Manipur, India and its neighbouring areas for the treatment of various ailments including cancer without considering the genotoxic effects. In an attempt to determine whether the aqueous extract of the plant leaves interact with genetic material both somatic and germinal were cytogenetically assayed. Mice which received intraperitoneal injection of the leave extract showed chromosome aberrations, abnormal chromosome behaviour and synaptonemal complex damages indicating their clastogenic potentials.
引用
收藏
页码：365 / 369
页数：5
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