Importance of Tranexamic acid in pharmacological taking care of bleeding in urological patients

Introduction - aim: Bleeding in urology is very important problem and it participates in mortality and morbidity of urological patients. It can be linked with empty system - hematuria, and also it can be developed outside of the empty system in retroperitoneal space. The bleeding requests quick diagnostic and therapy without delaying. The aim of work is to show positive output of pharmacological ageneses of antifibrinolytics in increased bloody drainage. Antifibrinolytics administration and useful effects are based on inhibition of proteolyses activity and prevention of lyses, actually on melting fibrinogen and fibrin, which makes possible reduction of bleeding level. Researches involved 50 patients who were under surgery treatment in Urological Clinic in Clinical Center Nis. All patients were prepared before intervention and anesthesiological risk was estimated according to ASA classification. Because of comorbidity according to the estimation of the risk factor they were given prophylactic doses of low molecular Heparin, two hours before surgical intervention together with monitoring screening of coagulation and D dimmer. All patients, who received Ugorol in intravenous way, were operatively treated. Postoperative bleeding in urology as an operative complication can be treated with antifibrinolytics. Short-term treatment with tranexamic acid is effective in reduction of operative and postoperative loss of blood. Decreasing of bleeding helps recovery, because the results of a better drainage lessen the risk of postoperative infection.