Synthesis of Multisubstituted Imidazoles via Copper-Catalyzed [3+2] Cycloadditions

被引：90

作者：

Tang, Dong

Wu, Ping

Liu, Xiang

Chen, Yong-Xin

Guo, Shuai-Bo

Chen, Wen-Lin

Li, Jia-Gen

Chen, Bao-Hua ^{[1
]}

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 06期

基金：

美国国家科学基金会;

关键词：

ONE-POT SYNTHESIS; SUBSTITUTED IMIDAZOLES; EFFICIENT; SYSTEM;

D O I：

10.1021/jo302555z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple route for the synthesis of imidazole derivatives via copper-catalyzed [3+2] cycloaddition reaction is described. This strategy has achieved high regioselectivity and used oxygen as an oxidant without the addition of expensive catalysts to provide moderate to good yields.

引用

页码：2746 / 2750

页数：5

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