Antiangiogenic Activity of Flavonoids from Melia azedarach

被引：0

作者：

Kumazawa, Shigenori ^{[1
]}

Kubota, Satomi ^{[1
]}

Yamamoto, Haruna ^{[1
]}

Okamura, Naoki ^{[1
]}

Sugiyama, Yasumasa ^{[2
]}

Kobayashi, Hirokazu ^{[1
]}

Nakanishi, Motoyasu ^{[3
]}

Ohta, Toshiro ^{[1
]}

机构：

[1] Univ Shizuoka, Dept Food & Nutr Sci, Suruga Ku, Shizuoka 4228526, Japan

[2] Kagoshima Univ, Fac Fisheries, Bioorgan Chem Res Grp, Kagoshima 8900056, Japan

[3] Shizuoka Univ, Innovat & Joint Res Ctr, Naka Ku, Hamamatsu, Shizuoka 4328561, Japan

来源：

NATURAL PRODUCT COMMUNICATIONS | 2013年 / 8卷 / 12期

关键词：

Angiogenesis; Flavonoid; Subcritical extraction; Melia azedarach; Quercetin; Kaempferol; QUERCETIN; ANGIOGENESIS; DISEASE;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three flavonoid glycosides, 1 (rutin: quercetin 3-O-rutinoside), 2 (kaempferol 3-O-robinobioside) and 3 (kaempferol 3-O-rutinoside) were isolated from the subcritical water extracts of Melia azedarach leaves. Strong antiangiogenic activity of these compounds was observed in the in vivo assay using the chorioallantoic membrane (CAM) from growing chick embryos.

引用

页码：1719 / 1720

页数：2

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