ANALYSIS OF HETEROPLASMY LEVEL IN MUTATIONS OF MITOCHONDRIAL DNA ASSOCIATED WITH ATHEROSCLEROSIS IN BUCCAL AND WHOLE BLOOD HUMAN CELLS

被引:0
|
作者
Sinyov, V. V. [1 ]
Sazonova, M. A. [2 ]
Ryzhkova, A. I. [3 ]
Barinova, V. A. [1 ]
Trubinov, S. S. [4 ]
Postnov, A. Y. [1 ]
Orekhov, A. N. [2 ]
Sobenin, I. A. [1 ]
机构
[1] Russian Cardiol Res & Prod Complex, Med Genet Lab, Moscow, Russia
[2] Inst Gen Pathol & Pathophysiol, Lab Cellular Mech Atherogenesis, Moscow, Russia
[3] KI Skryabin Moscow State Acad Vet Med & Biotechno, Dept Virol, Moscow, Russia
[4] Skolkovo Innovat Ctr, Atherosclerosis Res Inst, Med Genet Lab, Moscow, Russia
关键词
D O I
10.1016/j.atherosclerosis.2015.04.335
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
EAS-0353
引用
收藏
页码:E96 / E96
页数:1
相关论文
共 50 条
  • [41] Human Mesenchymal Stem Cells as a model for studying pathological mutations in mitochondrial DNA
    Llobet, L.
    Iglesias, E.
    Pacheu-Grau, D.
    Gomez-Duran, A.
    Emperador, S.
    Lopez-Gallardo, E.
    Montoya, J.
    Ruiz-Pesini, E.
    FEBS JOURNAL, 2012, 279 : 298 - 299
  • [42] Mitochondrial DNA mutations in human colonic crypt stem cells - implications for function
    Greaves, L
    Barron, M
    Taylor, R
    Turnbull, D
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2004, 1657 : 79 - 79
  • [43] The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations
    Taylor, RW
    Taylor, GA
    Durham, SE
    Turnbull, DM
    NUCLEIC ACIDS RESEARCH, 2001, 29 (15) : art. no. - e74
  • [44] Chronic atrial fibrillation associated with somatic mitochondrial DNA mutations in human atrial tissue
    Park, Hyung-Wook
    Ahn, Youngkeun
    Jeong, Myung-Ho
    Cho, Jeong-Gwan
    Park, Jong-Chun
    Kang, Jung-Chaee
    Shin, Myung-Geun
    Shin, Jong-Hee
    Suh, Soon-Pal
    Ryang, Dong-Wook
    Kim, Nam-Ho
    Choi, Jong-Bum
    Kim, Hye-Ran
    JOURNAL OF CLINICAL PATHOLOGY, 2007, 60 (08) : 948 - 950
  • [45] AGE-ASSOCIATED OXYGEN DAMAGE AND MUTATIONS IN MITOCHONDRIAL-DNA IN HUMAN HEARTS
    HAYAKAWA, M
    HATTORI, K
    SUGIYAMA, S
    OZAWA, T
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 189 (02) : 979 - 985
  • [46] Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues
    Fahn, HJ
    Wang, LS
    Kao, SH
    Chang, SC
    Huang, MH
    Wei, YH
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1998, 19 (06) : 901 - 909
  • [47] In silico analysis for predicting pathogenicity of five unclassified mitochondrial DNA mutations associated with mitochondrial cytopathies' phenotypes
    Bacalhau, Mafalda
    Pratas, Joao
    Simoes, Marta
    Mendes, Candida
    Ribeiro, Carolina
    Santos, Maria J.
    Diogo, Luisa
    Macario, Maria Carmo
    Grazina, Manuela
    EUROPEAN JOURNAL OF MEDICAL GENETICS, 2017, 60 (03) : 172 - 177
  • [48] Human buccal epithelial cells as a model system for molecular analysis of DNA, RNA and protein
    Danga, Ajay Kumar
    Rath, Pramod C.
    TISSUE & CELL, 2024, 88
  • [49] Single Nucleotide Polymorphism (SNP) analysis of DNA isolated from human buccal cells
    Dana, RC
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 : 393A - 393A
  • [50] Detection of the 4977 bp deletion of mitochondrial DNA in different human blood cells
    Mohamed, SA
    Wesch, D
    Blumenthal, A
    Bruse, P
    Windler, K
    Ernst, M
    Kabelitz, D
    Oehmichen, M
    Meissner, C
    EXPERIMENTAL GERONTOLOGY, 2004, 39 (02) : 181 - 188