Family-based tests of association and/or linkage

被引:0
|
作者
Whittaker, JC
Morris, AP
机构
[1] Univ Reading, Dept Appl Stat, Reading RG6 6FN, Berks, England
[2] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX4 7BN, England
关键词
D O I
10.1046/j.1469-1809.2001.6550407.x
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The large literature on family-based tests of association and/or linkage is reviewed, concentrating on the underlying principles and on recent methodological developments. We explain the distinction between testing for association and testing for linkage, and give our views on the circumstances in which each is the appropriate null hypothesis.
引用
收藏
页码:407 / 419
页数:13
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