A rapid and facile signal enhancement method for microcantilever-based immunoassays using the agglomeration of ferromagnetic nanoparticles

被引:5
|
作者
Lee, Dongkyu [1 ]
Kwon, Donghoon [1 ]
Ko, Wooree [1 ]
Joo, Jinmyoung [1 ]
Seo, Hyejung [2 ]
Lee, Soo Suk [2 ]
Jeon, Sangmin [1 ]
机构
[1] Pohang Univ Sci & Technol POSTECH, Dept Chem Engn, Pohang, South Korea
[2] Samsung Adv Inst Technol, Suwon, South Korea
基金
新加坡国家研究基金会;
关键词
MAGNETOMECHANICAL DETECTION; ASSAY;
D O I
10.1039/c2cc32400h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A rapid and facile signal enhancement method for detecting alpha-fetoprotein (AFP) was developed using the magnetic agglomeration of ferromagnetic nanoparticles and microcantilever sensors. The resonance frequency and deflection of the cantilevers were found to be more than 10-fold greater than that before physical agglomeration of the free nanoparticles around the magnetized nanoparticles.
引用
收藏
页码:7182 / 7184
页数:3
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