Cytokine-driven beta-cell production in vivo

被引：0
|
作者：
Worchel, Hannah N. [1 ,2 ]
Magnuson, Mark A. [1 ,2 ,3 ]
机构：
[1] Vanderbilt Univ, Ctr Stem Cell Biol, Nashville, TN 37235 USA
[2] Vanderbilt Univ, Dept Cell & Dev Biol, Nashville, TN 37235 USA
[3] Vanderbilt Univ, Dept Mol Physiol & Biophys, Nashville, TN 37232 USA
来源：
NATURE BIOTECHNOLOGY | 2014年 / 32卷 / 01期
关键词：
PANCREATIC ALPHA;
D O I：
10.1038/nbt.2788
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Transient treatment of diabetic mice with two cytokines induces acinar-to-beta-cell conversion to an extent sufficient to durably restore normoglycemia.
引用
收藏
页码：63 / 64
页数：2
相关论文
共 50 条
  • [31] Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin
    Barretto, Karina T.
    Swanson, Calvin M.
    Nguyen, Christopher L.
    Annis, Douglas S.
    Esnault, Stephane J.
    Mosher, Deane F.
    Johansson, Mats W.
    PLOS ONE, 2018, 13 (07):
  • [32] Plasminogen is a determinant of cytokine-driven inflammatory joint disease in mice
    Flick, MJ
    Thorton, S
    La Jeunesse, CM
    Talmage, KE
    Witte, DP
    Degen, JL
    THROMBOSIS AND HAEMOSTASIS, 2005, 93 (04) : A9 - A9
  • [33] Distinct cytokine-driven responses of activated blood γδ T cells:: Insights into unconventional T cell pleiotropy
    Vermijlen, David
    Ellis, Peter
    Langford, Cordelia
    Klein, Anne
    Engel, Rosel
    Willimann, Katharina
    Jomaa, Hassan
    Hayday, Adrian C.
    Eberl, Matthias
    JOURNAL OF IMMUNOLOGY, 2007, 178 (07): : 4304 - 4314
  • [34] RAT PANCREATIC BETA-CELL CULTURES AND INSULIN PRODUCTION
    SIRTORI, C
    LOMBARDO, C
    PAGANUZZI, M
    RUZZON, T
    GAETA, R
    GASLINI, 1980, 12 (01): : 77 - 80
  • [35] Beta-Cell Failure in Diabetic Glucotoxicity: Dedifferentiation and Redifferentiation In Vivo
    Wang, Zhiyu
    York, Nathan
    Nichols, Colin G.
    Remedi, Maria S.
    DIABETES, 2014, 63 : A81 - A82
  • [36] EFFECTS OF GLIBENCLAMIDE ON PANCREATIC BETA-CELL PROLIFERATION IN-VIVO
    GUIOT, Y
    HENQUIN, JC
    RAHIER, J
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1994, 261 (1-2) : 157 - 161
  • [37] Enhancing Pancreatic Beta-Cell Regeneration In Vivo with Pioglitazone and Alogliptin
    Yin, Hao
    Park, Soo-Young
    Wang, Xiao-Jun
    Misawa, Ryosuke
    Grossman, Eric J.
    Tao, Jing
    Zhong, Rong
    Witkowski, Piotr
    Bell, Graeme I.
    Chong, Anita S.
    PLOS ONE, 2013, 8 (06):
  • [38] Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis
    Steelant, Brecht
    Seys, Sven F.
    Van Gerven, Laura
    Van Woensel, Matthias
    Farre, Ricard
    Wawrzyniak, Paulina
    Krohn, Inge Kortekaas
    Bullens, Dominique M.
    Talavera, Karel
    Raap, Ulrike
    Boon, Louis
    Akdis, Cezmi A.
    Boeckxstaens, Guy
    Ceuppens, Jan L.
    Hellings, Peter W.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2018, 141 (03) : 951 - +
  • [39] Hemophagocytic lymphohistiocytosis (HLH): A heterogeneous spectrum of cytokine-driven immune disorders
    Brisse, Ellen
    Wouters, Carine H.
    Matthys, Patrick
    CYTOKINE & GROWTH FACTOR REVIEWS, 2015, 26 (03) : 263 - 280
  • [40] Previously Frozen Beta-Cell Transcriptional Response to Cytokine Treatment Mirrors That of Fresh Beta Cells
    Orchard, Peter
    Wang, Xiaoou
    Yan, Tingfen
    Narisu, Narisu
    Robertson, Cassie
    Erdos, Michael
    Meng, Jerry
    Collins, Francis S.
    Chen, Shuibing
    Parker, Stephen C.
    DIABETES, 2024, 73
12345