Conformation preferences in 2,4,6-trisubstituted heptanes

被引：7
|
作者：
Hoffmann, RW [1 ]
Stenkamp, D [1 ]
机构：
[1] Univ Marburg, Fachbereich Chem, D-35032 Marburg, Germany
来源：
TETRAHEDRON | 1999年 / 55卷 / 23期
关键词：
conformation; local conformer populations; syn-Pentane interactions;
D O I：
10.1016/S0040-4020(99)00349-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The preference of (2R*,4r*,6S*)-2,4,6-trichloroheptane (6) for populating the fully extended conformation mirrors the local conformational preferences of the 2,4-dichloropentane subunits. Likewise, the preference of (2R*,4r*,6S*)-2,6-dichloro-4-methyl-heptane (9) to populate the extended conformation mirrors that of the 2-chloro-4-methyl-heptane subunits. There is therefore no cooperative effect (neither positive nor negative) between the 2,4-disubstituted pentane subunits in determining the conformer preferences of the 2,4,6-trisubstituted heptanes studied. (C) Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：7169 / 7176
页数：8
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