The HDAC inhibitor, vorinastat, prevents TGF-β1 induced EMT and apoptosis in human renal proximal tubular cells

被引:0
|
作者
Hussain, Faryal [1 ]
Brimble, Elise [2 ]
Dickhout, Jeffrey G. [1 ,3 ]
机构
[1] McMaster Univ, Hamilton, ON, Canada
[2] Univ Toronto, Toronto, ON, Canada
[3] St Josephs HealthCare Hamilton, Hamilton, ON, Canada
来源
FASEB JOURNAL | 2013年 / 27卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
705.13
引用
收藏
页数:1
相关论文
共 50 条
  • [41] TGF-β regulation of tenascin gene expression in human proximal tubular epithelial cells.
    Lo, S
    Hazen-Martin, D
    Trojanowska, M
    MOLECULAR BIOLOGY OF THE CELL, 1999, 10 : 449A - 449A
  • [42] TGF-β1 stimulates movement of renal proximal tubular epithelial cells in a three-dimensional cell culture via an autocrine TGF-β2 production
    Luo, Deyi
    Guan, Qiunong
    Wang, Kunjie
    Nguan, Christopher Y. C.
    Du, Caigan
    EXPERIMENTAL CELL RESEARCH, 2017, 350 (01) : 132 - 139
  • [43] TGF-BETA-1 SECRETION BY HUMAN RENAL PROXIMAL TUBULAR CELLS (HPTC) IS STIMULATED BY BFGF
    PHILLIPS, AO
    STEADMAN, R
    TOPLEY, N
    WILLIAMS, JD
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 1995, 6 (03): : 906 - 906
  • [44] Snail1 suppresses TGF-β-induced apoptosis and is sufficient to trigger EMT in hepatocytes
    Franco, D. Lorena
    Mainez, Jessica
    Vega, Sonia
    Sancho, Patricia
    Murillo, Miguel M.
    de Frutos, Cristina A.
    del Castillo, Gaelle
    Lopez-Blau, Cristina
    Fabregat, Isabel
    Nieto, M. Angela
    JOURNAL OF CELL SCIENCE, 2010, 123 (20) : 3467 - 3477
  • [45] Promotion of USP4 to TGF-β1-induced EMT in renal tubular epithelial cells is regulated by AKT through stabilizing TβRI
    Zhou, J.
    Pu, J.
    Zhang, Y.
    Huang, Z.
    Wang, L.
    PEDIATRIC NEPHROLOGY, 2016, 31 (10) : 1739 - 1739
  • [46] 4-Hydroxy-2-hexenal-induced apoptosis in human renal proximal tubular epithelial cells
    Bae, Eun Hui
    Cho, Sunghee
    Joo, Soo Yeon
    Ma, Seong Kwon
    Kim, Suhn Hee
    Lee, JongUn
    Kim, Soo Wan
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2011, 26 (12) : 3866 - U669
  • [47] Liquiritin inhibits TGF-β1-induced epithelial mesenchymal transition and extracellular matrix deposition in human renal proximal tubular epithelial cells by suppressing the MAPK signaling
    Chen, Zhen
    Liu, Yi Jue
    Yu, Bo
    Li, Wei
    Zhang, Mengli
    Wu, Xian
    Gui, Feng
    Peng, Huan
    Ai, Fen
    MOLECULAR & CELLULAR TOXICOLOGY, 2024, 20 (03) : 641 - 647
  • [48] Oncostatin M inhibits TGF-β1-induced CTGF expression via STAT3 in human proximal tubular cells
    Sarkoezi, Rita
    Flucher, Kathrin
    Haller, Viktoria Maria
    Pirklbauer, Markus
    Mayer, Gert
    Schramek, Herbert
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 424 (04) : 801 - 806
  • [49] Aristolochic acid-I and aristolactam-I induced injury is mediated by TGF-β1 in renal proximal tubular epithelial cells.
    Li, XM
    Li, B
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 : 93A - 93A
  • [50] Independent control of TGF-β1 expression at the levels of transcription and translation in human proximal tubular epithelial cells.
    Fraser, DJ
    Phillips, AO
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 : 46A - 46A