Identification of the structural elements of P-REX1 required for activation by phosphatidylinositol 3,4,5-trisphosphate and G protein βγ dimers

被引:0
|
作者
Walliser, C [1 ]
Gierschik, P [1 ]
Illenberger, D [1 ]
机构
[1] Univ Ulm, Dept Pharmacol & Toxicol, D-89081 Ulm, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
190
引用
收藏
页码:R48 / R48
页数:1
相关论文
共 50 条
  • [1] Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gβγ subunits
    Hill, K
    Krugmann, S
    Andrews, SR
    Coadwell, WJ
    Finan, P
    Welch, HCE
    Hawkins, PT
    Stephens, LR
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (06) : 4166 - 4173
  • [2] PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 1 (P-REX1) IN INVASIVE MELANOMA
    Finn, A.
    Thomas, N.
    Pedone, K.
    Shields, J.
    Der, C.
    Groben, P.
    Lachiewicz, A.
    Hao, H.
    JOURNAL OF CUTANEOUS PATHOLOGY, 2009, 36 (01) : 161 - 161
  • [3] ACTIVATION OF PROTEIN-KINASE-C BY PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE
    SINGH, SS
    CHAUHAN, A
    BROCKERHOFF, H
    CHAUHAN, VPS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 195 (01) : 104 - 112
  • [4] Activation of phospholipase C-γ by phosphatidylinositol 3,4,5-trisphosphate
    Bae, YS
    Cantley, LG
    Chen, CS
    Kim, SR
    Kwon, KS
    Rhee, SG
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (08) : 4465 - 4469
  • [5] Differential sensitivity of P-Rex1 to isoforms of G protein βγ dimers
    Mayeenuddin, LH
    McIntire, WE
    Garrison, JC
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (04) : 1913 - 1920
  • [6] Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
    Stokoe, D
    Stephens, LR
    Copeland, T
    Gaffney, PRJ
    Reese, CB
    Painter, GF
    Holmes, AB
    McCormick, F
    Hawkins, PT
    SCIENCE, 1997, 277 (5325) : 567 - 570
  • [7] ACTIVATION OF THE ZETA-ISOZYME OF PROTEIN-KINASE-C BY PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE
    NAKANISHI, H
    BREWER, KA
    EXTON, JH
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (01) : 13 - 16
  • [8] Identification of protein kinase B (PKB) as a phosphatidylinositol 3,4,5-trisphosphate binding protein in Dictyostelium discoideum
    Tanaka, K
    Adachi, H
    Konishi, H
    Iwamatsu, A
    Ohkawa, K
    Shirai, T
    Nagata, S
    Kikkawa, U
    Fukui, Y
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1999, 63 (02) : 368 - 372
  • [9] Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation
    James, SR
    Downes, CP
    Gigg, R
    Grove, SJA
    Holmes, AB
    Alessi, DR
    BIOCHEMICAL JOURNAL, 1996, 315 : 709 - 713
  • [10] Specific interaction of Golgi coatomer protein α-COP with phosphatidylinositol 3,4,5-trisphosphate
    Chaudhary, A
    Gu, QM
    Thum, O
    Profit, AA
    Qi, Y
    Jeyakumar, L
    Fleischer, S
    Prestwich, GD
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (14) : 8344 - 8350