Dynamic in vivo 31P Magnetic Resonance Spectroscopy in Humans

被引:0
|
作者
Hajek, Milan [1 ]
Sedivy, Petr [1 ]
Kovar, Jan [1 ]
Dezortova, Monika [1 ]
机构
[1] Inst Clin & Expt Med, Dept Diagnost & Intervent Radiol, MR Unit, Prague, Czech Republic
来源
CHEMICKE LISTY | 2017年 / 111卷 / 08期
关键词
in vivo dynamic P-31 MR spectroscopy; muscular energy metabolism; pH; mitochondrial capacity; HUMAN SKELETAL-MUSCLE; ABSOLUTE QUANTIFICATION; FOREARM MUSCLE; ATP SYNTHESIS; EXERCISE; METABOLISM; DYSTROPHY; RECOVERY; LIVER; PH;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The constructions of super high (3T) and ultra high field (7T) magnetic resonance (MR) imagers in the past decade have enabled many MR imaging and spectroscopy experiments with other nuclei than protons. The paper summarizes the basis of in vivo dynamic P-31 MR spectroscopy for biomedical and clinical applications. The calculations of quantitative parameters of muscular metabolism, such as pH, mitochondrial capacity, ADP concentration, time constant of phosphocreatine recovery and others, are shown. The construction of ergometers for the whole body magnetic resonance systems is described. Examples of typical data processing and evaluation are demonstrated.
引用
收藏
页码:516 / 523
页数:8
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