Galectin-1 for Neuroprotection?

被引：17
|
作者：
Nonaka, Motohiro [1 ,2 ,3 ]
Fukuda, Minoru [1 ]
机构：
[1] Sanford Burnham Med Res Inst, Ctr Canc, Tumor Microenvironm Program, Glycobiol Unit, La Jolla, CA 92037 USA
[2] Ritsumeikan Univ, Res Ctr Glycobiotechnol, Shiga 5250058, Japan
[3] Japan Soc Promot Sci, Tokyo 1028472, Japan
来源：
IMMUNITY | 2012年 / 37卷 / 02期
关键词：
MULTIPLE-SCLEROSIS; IMMUNE;
D O I：
10.1016/j.immuni.2012.08.006
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Classically activated microglia (M1) are believed to play a key role in neuronal degeneration in multiple sclerosis (MS). In this issue of Immunity, Starossom et al. (2012) show that Galectin-1 exerts a neuroprotective function through glycosylation-dependent inactivation with M1 cells.
引用
收藏
页码：187 / 189
页数：3
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