New route to synthesis of unexpected 1,5-bis(1-benzofuran-2-yl)pentane-1,5-dione derivatives: Their structure determination with spectroscopic and X-ray methods

被引：3
|
作者：
Coskun, Demet [1 ]
机构：
[1] Firat Univ, Fac Sci, Dept Chem, TR-23119 Elazig, Turkey
来源：
JOURNAL OF MOLECULAR STRUCTURE | 2017年 / 1130卷
关键词：
Bisbenzofurandione; Michael addition; X-ray diffraction; IN-VITRO; ANTIMICROBIAL ACTIVITY; BIOLOGICAL EVALUATION; PART; BENZOFURAN; ANTICANCER; INHIBITORS;
D O I：
10.1016/j.molstruc.2016.10.063
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The new 1,5-bis(1-benzofuran-2-yl)-1,5-dione derivatives were obtained by the reaction of 2 -acetyl benzofuran derivatives (1a-b) and suitable aromatic aldehyde derivatives (2-pyridinecarboxaldehyde, 2-fluoro and 3-fluorobenzaldehyde) in the presence of sodium hydroxide as the base. Importantly, a new process was explored for the synthesis of new bis benzofuran dione derivatives. The structures of the compounds was identified with infrared (IR), H-1-NMR, C-13-NMR, HSQC and HMBC spectroscopic methods and elemental analysis. A representative X-ray crystallographic analysis of 3c was given, and its X-ray data were discussed in detail. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：455 / 462
页数：8
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