Risk factors for imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units in south China

被引:12
|
作者
Rao, Y. B. [1 ,2 ]
Ren, Z. X. [1 ,2 ]
Zhong, J. J. [1 ]
Zhong, X. M. [1 ,2 ]
Cao, B. [3 ]
Chen, D. M. [4 ]
Pan, X. N. [5 ]
Jia, Y. P. [6 ]
Gao, P. M. [7 ]
Yang, B. Y. [8 ]
Zhong, Q. [9 ]
Yang, J. [1 ]
机构
[1] Guangdong Women & Children Hosp, Dept Neonatol, Guangzhou, Guangdong, Peoples R China
[2] Guang Zhou Med Univ, Guangzhou, Guangdong, Peoples R China
[3] Women & Childrens Hosp Hunan Prov, Dept Neonatol, Changsha, Hunan, Peoples R China
[4] Women & Childrens Hosp Quanzhou, Dept Neonatol, Quanzhou, Fujian, Peoples R China
[5] Women & Childrens Hosp Guangxi Zhuang Autonomous, Dept Neonatol, Nanning, Guangxi, Peoples R China
[6] Womens & Childrens Hosp, Dept Neonatol, Haikou, Hainan, Peoples R China
[7] Women & Childrens Hosp Foshan, Dept Neonatol, Foshan, Guangdong, Peoples R China
[8] Women & Childrens Hosp Zhongshan, Dept Neonatol, Zhongshan, Guangdong, Peoples R China
[9] Women & Childrens Hosp Shenzhen, Dept Neonatol, Shenzhen, Guangdong, Peoples R China
关键词
Neonate; Pseudomonas aeruginosa; Imipenem; Hospital-acquired infection; NOSOCOMIAL INFECTION;
D O I
10.1016/j.jhin.2017.12.016
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This multi-centre retrospective study was designed to investigate the risk factors for infection with imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units (NICUs) in south China. All patients with confirmed P. aeruginosa infection from eight NICUs in south China were divided into two groups: imipenem-susceptible P. aeruginosa and imipenem-resistant P. aeruginosa. Data were analysed using Chi-squared test and logistic regression. In total, 188 medical records were reviewed. On multi-variate logistic analysis, the only independent risk factor was imipenem treatment within two weeks of isolation of P. aeruginosa (odds ratio 6.409, 95% confidence interval 1.926-21.333). (C) 2017 The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society.
引用
收藏
页码:305 / 308
页数:4
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