Enantioselective synthesis of β-amino esters and its application to the synthesis of the enantiomers of the antidepressant Venlafaxine

被引:50
|
作者
Davies, Huw M. L. [1 ]
Ni, Aiwu [1 ]
机构
[1] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
关键词
D O I
10.1039/b605047f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
beta-Amino esters are readily formed from the rhodium(II) prolinate-catalyzed intermolecular C - H insertion between methyl aryldiazoacetates and a bis-silyl protected methylamine.
引用
收藏
页码:3110 / 3112
页数:3
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