Post-Treatment Lyme Syndrome and Central Sensitization

被引：27

作者：

Batheja, Shweta

Nields, Jenifer A.

Landa, Alla

Fallon, Brian A. ^{[1
]}

机构：

[1] Columbia Univ, Dept Psychiat, New York, NY 10027 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2013年 / 25卷 / 03期

关键词：

CHRONIC-FATIGUE-SYNDROME; CENTRAL SENSITIVITY SYNDROMES; IRRITABLE-BOWEL-SYNDROME; BORRELIA-BURGDORFERI; TEMPORAL SUMMATION; CHRONIC PAIN; ANTIBIOTIC-TREATMENT; 2ND PAIN; FIBROMYALGIA; DISEASE;

D O I：

10.1176/appi.neuropsych.12090223

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Central sensitization is a process that links a variety of chronic pain disorders that are characterized by hypersensitivity to noxious stimuli and pain in response to non-noxious stimuli. Among these disorders, treatments that act centrally may have greater efficacy than treatments acting peripherally. Because many individuals with post-treatment Lyme syndrome (PTLS) have a similar symptom cluster, central sensitization may be a process mediating or exacerbating their sensory processing. This article reviews central sensitization, reports new data on sensory hyperarousal in PTLS, explores the potential role of central sensitization in symptom chronicity, and suggests new directions for neurophysiologic and treatment research.

引用

页码：176 / 186

页数：11

共 50 条

[11] A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing Immunologist
Wong, Katelyn H.
Shapiro, Eugene D.
Soffer, Gary K.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2022, 62 (01) : 264 - 271
[12] Dysautonomia following Lyme disease: a key component of post-treatment Lyme disease syndrome?
Adler, Brittany L.
Chung, Tae
Rowe, Peter C.
Aucott, John
FRONTIERS IN NEUROLOGY, 2024, 15
[13] Development of a foundation for a case definition of post-treatment Lyme disease syndrome
Aucott, John N.
Crowder, Lauren A.
Kortte, Kathleen B.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2013, 17 (06) : E443 - E449
[14] Cost of illness in patients with post-treatment Lyme disease syndrome in Belgium
Willems, Ruben
Verhaeghe, Nick
Perronne, Christian
Borgermans, Liesbeth
Annemans, Lieven
EUROPEAN JOURNAL OF PUBLIC HEALTH, 2023, 33 (04): : 668 - 674
[15] A distinct autoimmune signature in Post-treatment Lyme Disease Syndrome (PTLD)
Chen, Xin
Zhou, Xin
Wang, Haozhen
Ji, Xuhuai
Rebman, Alison
Soloski, Mark
Wagner, Christine
Snyder, Michael
Robinson, William
Aucott, John
Davis, Mark
JOURNAL OF IMMUNOLOGY, 2024, 212 (01):
[16] Metabolic Response in Patients With Post-treatment Lyme Disease Symptoms/Syndrome
Fitzgerald, Bryna L.
Graham, Barbara
Delorey, Mark J.
Pegalajar-Jurado, Adoracion
Islam, M. Nurul
Wormser, Gary P.
Aucott, John N.
Rebman, Alison W.
Soloski, Mark J.
Belisle, John T.
Molins, Claudia R.
CLINICAL INFECTIOUS DISEASES, 2021, 73 (07) : E2342 - E2349
[17] Myositis Autoantibodies in Patients with Suspected Post-Treatment Lyme Disease Syndrome
Sloupenska, Kristyna
Koubkova, Barbora
Horak, Pavel
Hutyrova, Beata
Racansky, Mojmir
Mares, Jan
Miklusova, Martina
Schovanek, Jan
Zapletalova, Jana
Raska, Milan
Krupka, Michal
LIFE-BASEL, 2023, 13 (02):
[18] The Persistent Lyme Disease: "True Chronic Lyme Disease" rather than "Post-treatment Lyme Disease Syndrome"
Lacout, Alexis
El Hajjam, Mostafa
Marcy, Pierre-Yves
Perronne, Christian
JOURNAL OF GLOBAL INFECTIOUS DISEASES, 2018, 10 (03) : 170 - 171
[19] Lyme disease and post-treatment Lyme disease syndrome: the neglected disease in our own backyard
Crowder, L. A.
Yedlin, V. A.
Weinstein, E. R.
Kortte, K. B.
Aucott, J. N.
PUBLIC HEALTH, 2014, 128 (09) : 784 - 791
[20] ASSESSING THE INCIDENCE AND TREATMENT OF POST-TREATMENT LYME DISEASE SYNDROME IN AN ADMINISTRATIVE CLAIMS DATABASE
Montejano, L. B.
VALUE IN HEALTH, 2014, 17 (03) : A267 - A267

← 1 2 3 4 5 →