Targeting Leukemia Initiating Cells by MUC1-C Subunit Inhibition

被引:3
|
作者
Stroopinsky, Dina [1 ]
Rosenblatt, Jacalyn [1 ]
Mills, Heidi [1 ]
Nardella, Caterina [1 ]
Ito, Keisuke [1 ]
Yin, Li [2 ]
Rajabi, Hasan [2 ]
Vasir, Baldev [2 ]
Kufe, Turner [1 ]
Luptakova, Katarina [1 ]
Arnason, Jon E. [1 ]
Levine, James D. [1 ]
Joyce, Robin [1 ]
Tzachanis, Dimitrios [1 ]
Boussiotis, Vassiliki A. [1 ]
Galinsky, Ilene [2 ]
Stone, Richard M. [2 ]
Reiter, Yoram [3 ]
Pandolfi, Pier Paolo [1 ]
Kufe, Donald [2 ]
Avigan, David [1 ]
机构
[1] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Technion Israel Inst Technol, Haifa, Israel
关键词
D O I
10.1182/blood.V120.21.3583.3583
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
3583
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Correction: MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells
    Hasan Rajabi
    Tsuyoshi Hata
    Wei Li
    Mark D. Long
    Qiang Hu
    Song Liu
    Deepak Raina
    Ling Kui
    Yota Yasumizu
    Deli Hong
    Mehmet Samur
    Donald Kufe
    Oncogene, 2019, 38 : 7278 - 7278
  • [42] Targeting the MUC1-C oncoprotein synergistically enhances cytotoxicity of breast carcinoma cells in combination with PI3K inhibitors
    Raina, Deepak
    Kharbanda, Surender
    Kufe, Donald
    CANCER RESEARCH, 2012, 72
  • [43] MUC1-C activates EZH2 expression and function in human cancer cells
    Rajabi, Hasan
    Hiraki, Masayuki
    Tagde, Ashujit
    Alam, Maroof
    Bouillez, Audrey
    Christensen, Camilla L.
    Samur, Mehmet
    Wong, Kwok-Kin
    Kufe, Donald
    SCIENTIFIC REPORTS, 2017, 7
  • [44] Androgen Receptor Regulates Expression of the MUC1-C Oncoprotein in Human Prostate Cancer Cells
    Rajabi, Hasan
    Joshi, Maya Datt
    Jin, Caining
    Ahmad, Rehan
    Kufe, Donald
    PROSTATE, 2011, 71 (12): : 1299 - 1308
  • [45] Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target
    Raina, Deepak
    Agarwal, Praveen
    Lee, James
    Bharti, Ajit
    McKnight, C. James
    Sharma, Pankaj
    Kharbanda, Surender
    Kufe, Donald
    PLOS ONE, 2015, 10 (08):
  • [46] MUC1-C Activates the BAF (mSWI/SNF) Complex in Prostate Cancer Stem Cells
    Hagiwara, Masayuki
    Yasumizu, Yota
    Yamashita, Nami
    Rajabi, Hasan
    Fushimi, Atsushi
    Long, Mark D.
    Li, Wei
    Bhattacharya, Atrayee
    Ahmad, Rehan
    Oya, Mototsugu
    Liu, Song
    Kufe, Donald
    CANCER RESEARCH, 2021, 81 (04) : 1111 - 1122
  • [47] Dependence on the MUC1-C Oncoprotein in Non-Small Cell Lung Cancer Cells
    Raina, Deepak
    Kosugi, Michio
    Ahmad, Rehan
    Panchamoorthy, Govind
    Rajabi, Hasan
    Alam, Maroof
    Shimamura, Takeshi
    Shapiro, Geoffrey I.
    Supko, Jeffrey
    Kharbanda, Surender
    Kufe, Donald
    MOLECULAR CANCER THERAPEUTICS, 2011, 10 (05) : 806 - 816
  • [48] MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells
    Kharbanda, Akriti
    Rajabi, Hasan
    Jin, Caining
    Alam, Maroof
    Wong, Kwok-Kin
    Kufe, Donald
    ONCOTARGET, 2014, 5 (19) : 8893 - 8905
  • [49] Dependence on MUC1-C in Progression of Neuroendocrine Prostate Cancer
    Kufe, Donald
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (04)
  • [50] Identification and characterization of agonist epitopes of the MUC1-C oncoprotein
    Jochems, Caroline
    Tucker, Jo A.
    Vergati, Matteo
    Boyerinas, Benjamin
    Gulley, James L.
    Schlom, Jeffrey
    Tsang, Kwong-Yok
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2014, 63 (02) : 161 - 174