Smart, biocompatible, responsive surfaces on pH, temperature and ionic strength of titanium oxide and niobium oxide with polymer brushes of poly (acrylic acid), poly(N-isopropylacrylamide) and poly([2-(methacryloyloxy) ethyl] trimethylammonium chloride)

被引:3
|
作者
Politakos, Nikolaos [1 ,2 ,3 ]
Diamanti, Eleftheria [1 ,4 ]
Moya, Sergio E. [1 ]
机构
[1] CIC biomaGUNE, Soft Matter Nanotechnol, Paseo Miramon 182 C, Donostia San Sebastian 20014, Spain
[2] Univ Basque Country UPV EHU, Joxe Mari Korta Ctr, POLYMAT, Avda Tolosa 72, Donostia San Sebastian 20018, Spain
[3] Univ Basque Country UPV EHU, Joxe Mari Korta Ctr, Fac Ciencias Quim, Dept Quim Aplicada, Avda Tolosa 72, Donostia San Sebastian 20018, Spain
[4] CIC nanoGUNE, Tolosa Hiribidea 76, E-20018 Donostia San Sebastian, Spain
关键词
Responsive surfaces; Titanium oxide; Niobium oxide; Polymer brushes; AFM; Biocompatibility; REVERSIBLE-ADDITION; RESISTANCE; BEHAVIOR; PROTEIN; ARCHITECTURE; FABRICATION; ADHESION; COMPLEX;
D O I
10.1016/j.eurpolymj.2019.01.018
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Titanium and Niobium oxide are metallic surfaces used as biomaterials due to their biocompatibility. Their improvement is very important in order to create smart surfaces in terms of responsiveness, with polymer brushes that have a switchable behavior in external stimulus of pH, temperature and ionic strength. The combination with poly(acrylic acid) - PAA, Poly(N-isopropylacrylamide) - PNiPAM and Poly([2-(methacryloyloxy) ethyl] trimethylammonium chloride) - PMETAC polymer brushes as long as their evaluation in biocompatibility and adhesion with cells can lead to smart surfaces that can be used as biomaterials.
引用
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页码:306 / 319
页数:14
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