A phase II study of trastuzumab-DM1, a first-in-class HER2 antibody-drug conjugate, in patients with HER2+metastatic breast cancer

被引:0
|
作者
Vukelja, S.
Rugo, H.
Vogel, C.
Borson, R.
Tan-Chiu, E.
Birkner, M.
Holden, S. N.
Klencke, B.
O'Shaughnessy, J.
Burris, H. A.
机构
[1] Tyler Canc Ctr, Tyler, TX USA
[2] UCSF Comprehens Canc Ctr, San Francisco, CA USA
[3] Lynn Canc Inst, Boca Raton, FL USA
[4] St Louis Canc & Breast Inst, St Louis, MO USA
[5] Genentech Inc, San Francisco, CA 94080 USA
[6] Baylor Sammons Canc Ctr, Dallas, TX USA
[7] Sarah Cannon Canc, Nashville, TN USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:71S / 71S
页数:1
相关论文
共 50 条
  • [41] BL-M07D1, a HER2 antibody-drug conjugate in subjects with locally advanced or metastatic HER2 expressing breast cancer and other solid tumors
    Song, E.
    Yao, H.
    Wang, Y.
    Zeng, Y.
    Sun, M. L.
    Zong, H.
    Lin, R.
    Wen, Z.
    Ding, R. M.
    Yu, J.
    Xiao, S.
    Wang, H.
    Zhu, H.
    Olivo, M. S.
    Zhu, Y.
    ANNALS OF ONCOLOGY, 2023, 34 : S478 - S479
  • [42] Bevacizumab plus trastuzumab for treatment of HER2+metastatic breast cancer
    De Amuriza Chicharro, N.
    Gastalver Martin, C.
    Goyache Goni, M. P.
    Cortijo Cascajares, S.
    Garcia Munoz, C.
    Ferrari Piquero, J. M.
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACY, 2013, 35 (05) : 984 - 985
  • [44] Responses to Subsequent Anti-HER2 Therapy after Treatment with Trastuzumab-DM1 in Women with HER2-Positive Metastatic Breast Cancer
    Olson, E. M.
    Lin, N. U.
    DiPiro, P. J.
    Najita, J.
    Krop, I. E.
    Winer, E. P.
    Burstein, H. J.
    CANCER RESEARCH, 2010, 70
  • [45] Predictors of survival in patients with HER2+metastatic breast cancer (MBC) treated with trastuzumab
    Olson, E. M.
    Najita, J. S.
    Sohl, J.
    Arnaout, A.
    Winer, E. P.
    Lin, N. U.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [46] Clinical Implications of Pathophysiological and Demographic Covariates on the Population Pharmacokinetics of Trastuzumab Emtansine, a HER2-Targeted Antibody-Drug Conjugate, in Patients With HER2-Positive Metastatic Breast Cancer
    Gupta, Manish
    LoRusso, Patricia M.
    Wang, Bei
    Yi, Joo-Hee
    Burris, Howard A., III
    Beeram, Muralidhar
    Modi, Shanu
    Chu, Yu-Waye
    Agresta, Samuel
    Klencke, Barbara
    Joshi, Amita
    Girish, Sandhya
    JOURNAL OF CLINICAL PHARMACOLOGY, 2012, 52 (05): : 691 - 703
  • [47] Population pharmacokinetics of trastuzumab emtansine, a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer: clinical implications of the effect of various covariates
    Lu, D.
    Girish, S.
    Gao, Y.
    Wang, B.
    Yi, J-H
    Guardino, E.
    Samant, M.
    Cobleigh, M.
    Rimawi, M.
    Conte, P.
    Jin, J.
    CANCER RESEARCH, 2012, 72
  • [48] Targeting HER2 with T-DM1, an Antibody Cytotoxic Drug Conjugate, is Effective in HER2 Over Expressing Bladder Cancer
    Hayashi, Tetsutaro
    Seiler, Roland
    Oo, Htoo Zarni
    Jaeger, Wolfgang
    Moskalev, Igor
    Awrey, Shannon
    Dejima, Takashi
    Todenhoefer, Tilman
    Li, Na
    Fazli, Ladan
    Matsubara, Akio
    Black, Peter C.
    JOURNAL OF UROLOGY, 2015, 194 (04): : 1120 - 1131
  • [49] Responses to subsequent anti-HER2 therapy after treatment with trastuzumab-DM1 in women with HER2-positive metastatic breast cancer
    Olson, E. M.
    Lin, N. U.
    DiPiro, P. J.
    Najita, J. S.
    Krop, I. E.
    Winer, E. P.
    Burstein, H. J.
    ANNALS OF ONCOLOGY, 2012, 23 (01) : 93 - 97
  • [50] N0337: Phase II study of capecitabine in combination with vinorelbine and trastuzumab for the first or second treatment of HER2+metastatic breast cancer
    Tan, W.
    Allred, J.
    Salim, M.
    Flynn, P.
    Kugler, J. W.
    Stella, P. J.
    Wiesenfeld, M.
    Bernath, A. M.
    Fitch, T. R.
    Perez, E. A.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)