Expressed hepatitis C virus NS5b RNA polymerase is a non-processive enzyme.

被引：0
|
作者：
Chung, RT
Han, CJ
Kaplan, LM
机构：
[1] MASSACHUSETTS GEN HOSP, GASTROINTESTINAL UNIT, BOSTON, MA 02114 USA
[2] HARVARD UNIV, SCH MED, BOSTON, MA USA
来源：
GASTROENTEROLOGY | 1997年 / 112卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：A1244 / A1244
页数：1
相关论文
共 50 条
  • [21] A review on an update of NS5B polymerase hepatitis C virus inhibitors
    Varshney, J.
    Sharma, P. K.
    Sharma, A.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2012, 16 (05) : 667 - 671
  • [22] Specific interaction between the hepatitis C virus NS5B RNA polymerase and the 3′ end of the viral RNA
    Cheng, JC
    Chang, MF
    Chang, SC
    JOURNAL OF VIROLOGY, 1999, 73 (08) : 7044 - 7049
  • [23] NS5B RNA Dependent RNA Polymerase Inhibitors: The Promising Approach to Treat Hepatitis C Virus Infections
    Deore, R. R.
    Chern, J. -W.
    CURRENT MEDICINAL CHEMISTRY, 2010, 17 (32) : 3806 - 3826
  • [24] Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin
    Maag, D
    Castro, C
    Hong, Z
    Cameron, CE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (49) : 46094 - 46098
  • [25] De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus
    Luo, GX
    Hamatake, RK
    Mathis, DM
    Racela, J
    Rigat, KL
    Lemm, J
    Colonno, RJ
    JOURNAL OF VIROLOGY, 2000, 74 (02) : 851 - 863
  • [26] Expression of hepatitis C virus NS5B protein: Characterization of its RNA polymerase activity and RNA binding
    Ishii, K
    Tanaka, Y
    Yap, CC
    Aizaki, H
    Matsuura, Y
    Miyamura, T
    HEPATOLOGY, 1999, 29 (04) : 1227 - 1235
  • [27] Activation of hepatitis C virus NS5b RNA polymerase activity by host cell factors.
    Han, CJ
    Chung, RT
    Kaplan, LM
    GASTROENTEROLOGY, 1997, 112 (04) : A1277 - A1277
  • [28] Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition
    Solbak, Sara M. O.
    Abdurakhmanov, Eldar
    Vedeler, Anni
    Danielson, U. Helena
    VIROLOGY JOURNAL, 2017, 14
  • [29] Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase
    Sofia, Michael J.
    Chang, Wonsuk
    Furman, Phillip A.
    Mosley, Ralph T.
    Ross, Bruce S.
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (06) : 2481 - 2531
  • [30] Hepatitis C virus core protein binds to a C-terminal region of NS5B RNA polymerase
    Uchida, M
    Hino, N
    Yamanaka, T
    Fukushima, H
    Imanishi, T
    Uchiyama, Y
    Kodama, T
    Doi, T
    HEPATOLOGY RESEARCH, 2002, 22 (04) : 297 - 306
12345