A digital twin for 64Cu production with cyclotron and solid target system

被引:6
|
作者
Isolan, Lorenzo [1 ,2 ]
Malinconico, Mario [3 ]
Tieu, William [4 ]
Hollis, Courtney [5 ]
Testa, Marco [3 ]
Melandri, Matteo [3 ]
Brunetti, Alessandro [3 ]
Sumini, Marco [1 ,2 ]
机构
[1] Univ Bologna, Ind Engn Dept, Montecuccolino Lab, Via Colli 16, I-40136 Bologna, BO, Italy
[2] Natl Inst Nucl Phys INFN, Viale C Berti Pichat 6-2, I-40127 Bologna, BO, Italy
[3] COMECER, Via Maestri Lavoro 90, I-48014 Castel Bolognese, RA, Italy
[4] Univ Adelaide, Adelaide, SA 5005, Australia
[5] South Australian Hlth & Med Res Inst SAHMRI, Mol Imaging & Therapy Res Unit MITRU, Adelaide, SA 5000, Australia
关键词
JADE;
D O I
10.1038/s41598-022-23048-5
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
One method for finding reliable and cost-effective solutions for designing radioisotope production systems is represented by the "digital twin" philosophy of design. Looking at cyclotron solid targets, uncertainties of the particle beam, material composition and geometry play a crucial role in determining the results. The difference between what has been designed and what can be effectively manufactured, where processes such as electroplating are poorly controllable and generate large non-uniformities in deposition, must also be considered. A digital twin, where the target geometry is 3D scanned from real models, can represent a good compromise for connecting "ideal" and "real" worlds. Looking at the Ni-64(p,n)Cu-64 reaction, different Unstructured-Mesh MCNP6 models have been built starting from the 3D solid target system designed and put into operation by COMECER. A characterization has been performed considering the designed ideal target and a 3D scan of a real manufactured target measured with a ZEISS contact probe. Libraries and physics models have been also tested due to limited cross-section data. Proton spectra in the target volume, 3D proton-neutron-photon flux maps, average energies, power to be dissipated, shut-down dose-rate, Cu-64 yield compared with various sources of experimental data and beam axial shifting impact, have been estimated. A digital twin of the Ni-64(p,n)Cu-64 production device has been characterized, considering the real measured target geometry, paving the way for a fully integrated model suitable also for thermal, structural or fluid-dynamic analyses.
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页数:11
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