Direct Monte Carlo computation of time-resolved fluorescence in heterogeneous turbid media

被引：10
|
作者：
Kumar, Anand T. N. [1 ]
机构：
[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp,Dept Radiol, Athinoula A Martinos Ctr Biomed Imaging, Charlestown, MA 02129 USA
来源：
OPTICS LETTERS | 2012年 / 37卷 / 22期
基金：
美国国家卫生研究院;
关键词：
PHOTON MIGRATION; TISSUES; TOMOGRAPHY; SIMULATION;
D O I：
10.1364/OL.37.004783
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We show that a multiexponential model for time-resolved fluorescence allows the use of an absorption-perturbation Monte Carlo (MC) approach based on stored photon path histories. This enables the rapid fitting of fluorescence yield, lifetimes, and background tissue absorptions in complex heterogeneous media within a few seconds, without the need for temporal convolutions or MC recalculation of photon path lengths. We validate this method using simulations with both a slab and a heterogeneous model of the mouse head. (C) 2012 Optical Society of America
引用
收藏
页码：4783 / 4785
页数：3
相关论文
共 50 条
  • [21] Monte Carlo characterization of parallelized fluorescence confocal systems imaging in turbid media
    Tanbakuchi, Anthony A.
    Rouse, Andrew R.
    Gmitro, Arthur F.
    JOURNAL OF BIOMEDICAL OPTICS, 2009, 14 (04)
  • [22] Hybrid Monte Carlo simulation with ray tracing for fluorescence measurements in turbid media
    Lee, Seung Yup
    Mycek, Mary-Ann
    OPTICS LETTERS, 2018, 43 (16) : 3846 - 3849
  • [23] Time-resolved optical fluorescence spectroscopy of heterogeneous turbid media with special emphasis on brain tissue structures including diseased regions: A sensitivity analysis
    Vaudelle, Fabrice
    L'huillier, Jean-Pierre
    OPTICS COMMUNICATIONS, 2013, 304 : 161 - 168
  • [24] Direct measurement of axial distribution of absorbed optical energy in turbid media by time-resolved optoacoustic method
    Karabutov, AA
    Podymova, NB
    Pelivanov, IM
    Skipetrov, SE
    Oraevsky, AA
    BIOMEDICAL OPTOACOUSTICS, 2000, 3916 : 112 - 121
  • [25] Polarized light propagation through scattering media: time-resolved Monte Carlo simulations and experiments
    Wang, XD
    Wang, LHV
    Sun, CW
    Yang, CC
    JOURNAL OF BIOMEDICAL OPTICS, 2003, 8 (04) : 608 - 617
  • [26] Investigation of two-layered turbid media with time-resolved reflectance
    Kienle, A
    Glanzmann, T
    Wagnieres, G
    van den Bergh, H
    APPLIED OPTICS, 1998, 37 (28): : 6852 - 6862
  • [27] Maximum likelihood methods for time-resolved imaging through turbid media
    Eriksson, Brian
    Nowak, Robert
    2006 IEEE INTERNATIONAL CONFERENCE ON IMAGE PROCESSING, ICIP 2006, PROCEEDINGS, 2006, : 641 - +
  • [28] Time-resolved subtraction method for measuring optical properties of turbid media
    Milej, Daniel
    Abdalmalak, Androu
    Janusek, Dariusz
    Diop, Mamadou
    Liebert, Adam
    St Lawrence, Keith
    APPLIED OPTICS, 2016, 55 (07) : 1507 - 1513
  • [29] Propagation of polarized light in birefringent turbid media: time-resolved simulations
    Wang, XD
    Wang, LHV
    OPTICS EXPRESS, 2001, 9 (05): : 254 - 259
  • [30] Time-resolved propagation of polarized light in turbid media: experiment and theory
    Wang, XD
    Sun, CW
    Kiang, YW
    Yang, CC
    Wang, LV
    LASER TISSUE INTERACTION XIII: PHOTOCHEMICAL, PHOTOTHERMAL, AND PHOTOMECHANICAL, 2002, 4617 : 204 - 207
12345