Urothelial carcinoma with squamous differentiation-The pathologists' perspective

被引:21
|
作者
Gellert, Lan L. [1 ]
Warrick, Joshua [2 ]
Al-Ahmadie, Hikmat A. [3 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Pathol, Nashville, TN 37232 USA
[2] Penn State Univ, Milton S Hershey Med Ctr, Dept Pathol, Hershey, PA 17033 USA
[3] Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10021 USA
关键词
Urothelial carcinoma; Squamous differentiation; Squamous cell carcinoma; Variant histology; Molecular subtypes; DIVERGENT HISTOLOGIC DIFFERENTIATION; MOLECULAR-WEIGHT CYTOKERATIN; CELL-CARCINOMA; BLADDER-CANCER; PROSTATE ADENOCARCINOMA; HUMAN-PAPILLOMAVIRUS; IMMUNOHISTOCHEMICAL EVALUATION; RADICAL CYSTECTOMY; POTENTIAL UTILITY; UROPLAKIN-III;
D O I
10.1016/j.urolonc.2015.07.018
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Squamous differentiation is the most common variant histology in urothelial carcinoma and may have effects on clinical outcome. Inconsistencies in reporting variant histologies in urothelial carcinoma are well documented. Immunohistochemical and molecular markers may help identify tumors with squamous differentiation beyond light microscopy. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:437 / 443
页数:7
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