Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial

被引:35
|
作者
Meeuwsen, Els [1 ]
Melis, Rene [1 ]
van der Aa, Geert [2 ]
Goluke-Willemse, Gertie [3 ]
de Leest, Benoit [4 ]
van Raak, Frank [5 ]
Scholzel-Dorenbos, Carla [6 ]
Verheijen, Desiree [7 ]
Verhey, Frans [8 ]
Visser, Marieke [9 ]
Wolfs, Claire [8 ]
Adang, Eddy [10 ]
Rikkert, Marcel Olde [1 ]
机构
[1] Radboud Univ Nijmegen, Nijmegen Med Ctr, Radboud Alzheimer Ctr, Dept Geriatr, Nijmegen, Netherlands
[2] Catharina Hosp, Dept Geriatr, Eindhoven, Netherlands
[3] Rijnstate Hosp, Dept Geriatr, Arhem, Netherlands
[4] Elkerliek Hosp, Dept Geriatr, Helmond, Netherlands
[5] Ctr Land van Cuijk, Mental Hlth Org Oost Brabant, Boxmeer, Netherlands
[6] Slingeland Hosp, Dept Geriatr, Doetinchem, Netherlands
[7] Gelderse Vallei Hosp, Dept Geriatr, Ede, Netherlands
[8] Maastricht Univ Med Ctr, Alzheimer Ctr Limburg, Dept Psychiat & Neuropsychol, Maastricht, Netherlands
[9] Vrije Univ Amsterdam Med Ctr, Alzheimer Ctr Amsterdam, Dept Neurol, Amsterdam, Netherlands
[10] Radboud Univ Nijmegen, Nijmegen Med Ctr, Dept Epidemiol Biostat & Hlth Technol Assessment, Nijmegen, Netherlands
来源
PLOS ONE | 2013年 / 8卷 / 11期
关键词
ALZHEIMERS-DISEASE; STRATEGY; VALUATIONS; EUROQOL; UTILITY; TARIFF; STATE;
D O I
10.1371/journal.pone.0079797
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objective: To evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners' care. Methods: A multicentre randomised trial with 175 community dwelling patients newly diagnosed with mild to moderate dementia, and their informal caregivers, with twelve months' follow-up. Cost-effectiveness was evaluated from a societal point of view and presented as incremental cost per quality adjusted life year. To establish cost-effectiveness, a cost-utility analysis was conducted using utilities based on the EQ-5D. Uncertainty surrounding the incremental cost-effectiveness ratio (difference in costs divided by difference in effects) was calculated by bootstrapping from the original data. Results: Compared to general practitioners' care, treatment by the memory clinics was on average (sic)1024 (95% CI: -(sic)7723 to (sic)5674) cheaper, and showed a non-significant decrease of 0.025 (95% CI: -0.114 to 0.064) quality adjusted life years. The incremental cost-effectiveness point estimate from the bootstrap simulation was (sic) 41 442 per QALY lost if one would use memory clinic care instead of general practitioner care. Conclusion: No evidence was found that memory clinics were more cost-effective compared to general practitioners with regard to post-diagnosis treatment and coordination of care of patients with dementia in the first year after diagnosis.
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收藏
页数:7
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