The increasing size of swine farms poses an environmental risk to water bodies, considering that manure is generally applied to croplands without appropriate agronomic criteria. Objective: the present work aimed to evaluate various chemical changes occurring in soils fertirrigated with filtrated wastewater from swine facilities (FWS). Methods: 21 drainage lysimeters filled with Dystrophic Red-Yellow Latossoil were cultivated with tomato plants in protected environments, and fertirrigated with several doses of FWS, with and without fertilizer addition. Treatments were: T1: control (provided the recommended irrigation and fertilization needs for tomato plants). Treatments T2, T3, and T4, provided 100, 150, and 200% of recommended nitrogen (N), respectively, by adding filtered swine wastewater. Treatments T5, T6, and T7 provided equivalent N percentages with fertilizer addition. The experiment was conducted in a completely randomized design (seven treatments and three replications). Results: compared with initial conditions, an increase in the concentration of available phosphorus was observed, mainly in the superficial layers. The FWS addition resulted in increments in N concentration in the superficial layers, while chemical fertilizer application resulted in larger displacements in the soil profile. Conclusion: chemical fertilization was more effective than FWS for ionizing the soil solution.