Does Feeding Tube Insertion and Its Timing Improve Survival?

被引:114
|
作者
Teno, Joan M. [1 ]
Gozalo, Pedro L. [1 ]
Mitchell, Susan L. [2 ]
Kuo, Sylvia [1 ]
Rhodes, Ramona L. [3 ]
Bynum, Julie P. W. [4 ]
Mor, Vincent [1 ]
机构
[1] Brown Univ, Ctr Gerontol & Hlth Care Res, Warren Alpert Sch Med, Providence, RI 02912 USA
[2] Hebrew SeniorLife Inst Aging Res, Boston, MA USA
[3] Univ Texas SW Med Ctr Dallas, Dallas, TX 75390 USA
[4] Dartmouth Coll, Hitchcock Med Ctr, Dartmouth Med Sch, Dartmouth Inst, Hanover, NH 03756 USA
关键词
feeding tubes; timing of insertion; eating problems; dementia; survival; PERCUTANEOUS ENDOSCOPIC GASTROSTOMY; NURSING-HOME RESIDENTS; MARGINAL STRUCTURAL MODELS; ADVANCED DEMENTIA; MORTALITY;
D O I
10.1111/j.1532-5415.2012.04148.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objectives To examine survival with and without a percutaneous endoscopic gastrostomy (PEG) feeding tube using rigorous methods to account for selection bias and to examine whether the timing of feeding tube insertion affected survival. Design Prospective cohort study. Setting All U.S. nursing homes (NHs). Participants Thirty-six thousand four hundred ninety-two NH residents with advanced cognitive impairment from dementia and new problems eating studied between 1999 and 2007. Measurements Survival after development of the need for eating assistance and feeding tube insertion. Results Of the 36,492 NH residents (88.4% white, mean age 84.9, 87.4% with one feeding tube risk factor), 1,957 (5.4%) had a feeding tube inserted within 1 year of developing eating problems. After multivariate analysis correcting for selection bias with propensity score weights, no difference was found in survival between the two groups (adjusted hazard ratio (AHR) = 1.03, 95% confidence interval (CI) = 0.941.13). In residents who were tube-fed, the timing of PEG tube insertion relative to the onset of eating problems was not associated with survival after feeding tube insertion (AHR = 1.01, 95% CI = 0.861.20, persons with a PEG tube inserted within 1 month of developing an eating problem versus later (4 months) insertion). Conclusion Neither insertion of PEG tubes nor timing of insertion affect survival.
引用
收藏
页码:1918 / 1921
页数:4
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