A Convenient Synthesis of C-3-Aryloxymethyl Imidazo[1,2-a]Pyridine Derivatives

被引:3
|
作者
Kona, Sridevi [1 ]
Ravi, Rama Suresh [1 ]
Chava, Venkata N. R. [2 ]
Perali, Ramu Sridhar [1 ]
机构
[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India
[2] AG & SG Siddhartha Arts & Sci Coll, Dept Chem, Vuyyuru 521165, Andhra Pradesh, India
关键词
TOSYLHYDRAZONES; GENERATION; LIGANDS;
D O I
10.1155/2013/296792
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Imidazo[1,2-a]pyridine-based tosylhydrazone was prepared and treated with K2CO3 in dioxane at 110 degrees C to generate the corresponding carbene in situ. It was coupled with a variety of aryl alcohols in one pot to obtain a series of imidazo[1,2-a]pyridine derivatives possessing aryl ether moiety at C-3 position.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] Strategies for Synthesis of Imidazo[1,2-a]pyridine Derivatives: Carbene Transformations or C-H Functionalizations
    Yu, Yue
    Su, Zhengquan
    Cao, Hua
    CHEMICAL RECORD, 2019, 19 (10): : 2105 - 2118
  • [22] Medicinal Attributes of Imidazo[1,2-a] pyridine Derivatives: An Update
    Devi, Nisha
    Singh, Dharmender
    Rawal, Ravindra K.
    Bariwal, Jitender
    Singh, Virender
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2016, 16 (26) : 2963 - 2994
  • [23] PREPARATION OF SOME SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE DERIVATIVES
    SHAWCROSS, AP
    STANFORTH, SP
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1993, 30 (02) : 563 - 565
  • [24] CHEMISTRY OF DICHLOROMALEIMIDES .3. SYNTHESIS AND PHARMACOLOGY OF IMIDAZO- 1,2-A!PYRIDINE DERIVATIVES - MEDI
    KARTEN, MJ
    PATEL, GS
    SCHWINN, A
    WEINBERG, ED
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1970, : 29 - &
  • [25] A convenient synthesis of novel substituted imidazo[1,2-a][1,5] benzodiazepine derivatives
    Kosychova, Lidija
    Pleckaitiene, Lina
    Staniulyte, Zita
    Janciene, Regina
    Palaima, Algirdas
    Puodziunaite, Benedikta D.
    ARKIVOC, 2006, : 158 - 164
  • [26] Synthesis and antitubercular evaluation of reduced lipophilic imidazo [1,2-a]pyridine-3-carboxamide derivatives
    Wang, Hongjian
    Wang, Apeng
    Gu, Jian
    Fu, Lei
    Lv, Kai
    Ma, Chao
    Tao, Zeyu
    Wang, Bin
    Liu, Mingliang
    Guo, Huiyuan
    Lu, Yu
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 165 : 11 - 17
  • [27] Design, synthesis and antimycobacterial activity of novel imidazo[1,2-a]pyridine-3-carboxamide derivatives
    Lv, Kai
    Li, Linhu
    Wang, Bo
    Liu, Mingliang
    Wang, Bin
    Shen, Weiyi
    Guo, Huiyuan
    Lu, Yu
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 137 : 117 - 125
  • [28] Short and efficient access to imidazo[1,2-a]pyrrolo[3,2-c]pyridine derivatives
    Gaumet, Vincent
    Moreau, Emmanuel
    Taleb, Abbass
    Leal, Fernand
    Neyts, Johan
    Paeshuyse, Jan
    Lartigue, Claire
    Chavignon, Olivier
    Gueiffier, Alain
    Teulade, Jean-Claude
    Metin, Jacques
    Chezal, Jean-Michel
    TETRAHEDRON LETTERS, 2010, 51 (47) : 6082 - 6085
  • [29] Regiospecific synthesis of 3-substituted imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrimidines, and imidazo[1,2-c]pyrimidine
    Katritzky, AR
    Xu, YJ
    Tu, HB
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (12): : 4935 - 4937
  • [30] Synthesis and antimicrobial screening of novel series of imidazo-[1,2-a]pyridine derivatives
    Desai, N. C.
    Pandya, M. R.
    Rajpara, K. M.
    Joshi, V. V.
    Vaghani, H. V.
    Satodiya, H. M.
    MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (12) : 4437 - 4446