Toxigenic Clostridium difficile PCR ribotypes in edible marine bivalve molluscs in Italy

被引：35

作者：

Troiano, Tiziana ^{[1
]}

Harmanus, Celine ^{[2
]}

Sanders, Ingrid M. J. G. ^{[2
]}

Pasquale, Vincenzo ^{[1
]}

Dumontet, Stefano ^{[1
]}

Capuano, Federico ^{[3
]}

Romano, Vincenza ^{[1
]}

Kuijper, Ed J. ^{[2
]}

机构：

[1] Parthenope Univ Naples, Dept Sci & Technol, I-80143 Naples, Italy

[2] Leiden Univ, Med Ctr, Natl Reference Lab Clostridium Difficile, Dept Med Microbiol, NL-2300 RC Leiden, Netherlands

[3] Ist Zooprofilatt Sperimentale Mezzogiorno Portici, Dept Food Inspect, I-80055 Naples, Italy

来源：

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY | 2015年 / 208卷

关键词：

Clostridium difficile; Edible bivalve mollusc; Fidaxomicin; LFF571; GENOTYPIC CHARACTERIZATION; GEL-ELECTROPHORESIS; PREVALENCE; MEAT; EPIDEMIOLOGY; INFECTION; PRODUCTS; SEAFOOD; LFF571; TOXIN;

D O I：

10.1016/j.ijfoodmicro.2015.05.002

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Even though food of animal sources and different foodstuffs are well known to be potentially carrier of Clostridium difficile, few data are available on the occurrence of C. difficile in seafood. This work investigated the occurrence of C. difficile in edible bivalve molluscs in southern Italy. Out of the 925 investigated samples, 3.9% contained C. difficile. Eighteen strains harboured both genes for toxins A and B whereas 1 only had toxin B gene. Binary toxin genes were found in 22.2% of the isolates. The most frequently ribotypes found were 078/126 (22.2%), 010 (19.4%), and 001 (83%). All isolates were susceptible to metronidazole, vancomycin, fidaxomicin, and to the new semisynthetic thiopeptide antibiotic LFF571, whereas 19.4% of them were resistant to moxifloxacin, 30.5% to clindamycin, 38.8% to erythromycin, and 100% to ciprofloxacin. This study points out that edible molluscs could be a potential source of toxigenic C difficile ribotypes and a potential risk for human health. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：30 / 34

页数：5

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