A linaclotide phase 3 trial in chronic constipation (CC): randomized withdrawal period results

被引：0
|
作者：
Johnston, J. M. [1 ]
Schneier, H. [2 ]
Lavins, B. J. [1 ]
Shiff, S. J. [2 ]
Macdougall, J. E. [1 ]
Kurtz, C. B. [1 ]
Currie, M. G. [1 ]
Lembo, A. J. [3 ]
机构：
[1] Ironwood Pharmaceut Inc, Cambridge, MA USA
[2] Forest Res Inst, Jersey City, NJ USA
[3] Beth Israel Deaconess Med Ctr, Div Gastroenterol, Boston, MA 02215 USA
来源：
NEUROGASTROENTEROLOGY AND MOTILITY | 2010年 / 22卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
41
引用
收藏
页码：13 / 13
页数：1
相关论文
共 50 条
  • [41] Plecanatide Is Effective and Safe in the Treatment for Chronic Idiopathic Constipation: Results of a Phase II Trial
    Charles Barish
    Spencer Dorn
    Ronald P. Fogel
    Reema Patel
    Jonathan Rosenberg
    Digestive Diseases and Sciences, 2021, 66 : 537 - 540
  • [42] Efficacy of Linaclotide in Type II Diabetics With Chronic Constipation: A Randomized, Double-Blind, Placebo-Controlled, and Cross-Over Trial
    Shankar, Nagasri
    Bright, Tamis
    Liu, Roy
    Gomez, Yvette
    Quezada, Anahi
    Alvarado, Ben
    Bashashati, Mohammad
    Sarosiek, Jerzy
    McCallum, Richard W.
    Sarosiek, Irene
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2017, 112 : S57 - S57
  • [43] Psychometric evaluation of patient-reported outcome measures for assessing chronic constipation symptom severity and change: Results from Phase 2b and Phase 3 trials of Linaclotide
    Nelson, L. M.
    Williams, V. S. L.
    Fehnel, S. E.
    Tourkodimitris, S.
    Baird, M. J.
    Carson, R. T.
    Johnston, J. M.
    NEUROGASTROENTEROLOGY AND MOTILITY, 2012, 24 : 180 - 180
  • [44] Psychometric Evaluation of Patient-Reported Outcome Measures for Assessing Chronic Constipation Symptom Severity and Change: Results From Phase 2b and Phase 3 Trials of Linaclotide
    Nelson, Lauren
    Williams, Valerie
    Fehnel, Sheri
    Tourkodimitris, Stavros
    Baird, Mollie
    Carson, Robyn
    Johnston, Jeffrey
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2012, 107 : S587 - S588
  • [45] DOSE-FINDING OF LINACLOTIDE FOR PATIENTS WITH CHRONIC CONSTIPATION IN JAPAN: A PHASE II RANDOMIZED, DOUBLE-BLIND, AND PLACEBO-CONTROLLED STUDY
    Fukudo, Shin
    Miwa, Hiroto
    Nakajima, Atsushi
    Kinoshita, Yoshikazu
    Kosako, Masanori
    Nakagawa, Ayako
    Akiho, Hiraku
    Kuroishi, Kentarou
    Johnston, Jeffrey M.
    Currie, Mark
    Ohkusa, Toshifumi
    GASTROENTEROLOGY, 2017, 152 (05) : S515 - S516
  • [46] IMPACT OF LINACLOTIDE ON WORK PRODUCTIVITY AND DAILY ACTIVITY IMPAIRMENT AMONG ADULTS WITH IRRITABLE BOWEL SYNDROME WITH CONSTIPATION: RESULTS FROM A 26-WEEK PHASE 3 TRIAL
    Buono, J. L.
    Tourkodimitris, S.
    Sarocco, P.
    Johnston, J. M.
    Carson, R. T.
    VALUE IN HEALTH, 2014, 17 (03) : A38 - A39
  • [47] Efficacy and Safety of Once Daily Linaclotide Administered Orally for 12-Weeks in Patients With Chronic Constipation: Results From 2 Randomized, Double-Blind, Placebo-Controlled Phase 3 Trials
    Lembo, Anthony
    Schneier, Harvey
    Lavins, Bernard J.
    Shiff, Steven J.
    MacDougall, James E.
    Jia, Xinwei D.
    Kurtz, Caroline B.
    Currie, Mark G.
    Johnston, Jeffrey M.
    GASTROENTEROLOGY, 2010, 138 (05) : S53 - S54
  • [48] Sustainability of Linaclotide Response in Chronic Idiopathic Constipation Patients: A Post-hoc Pooled Analysis of Two Phase 3 Trials
    Lavins, Bernard J.
    Fox, Susan M.
    Reasner, David
    Tripp, Kenneth
    Shea, Elizabeth P.
    Blakesley, Rick
    Shiff, Steven
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2015, 110 : S746 - S747
  • [49] A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic Constipation
    Miner, Philip B., Jr.
    Koltun, William D.
    Wiener, Gregory J.
    De la Portilla, Marianela
    Prieto, Blas
    Shailubhai, Kunwar
    Layton, Mary Beth
    Barrow, Laura
    Magnus, Leslie
    Griffin, Patrick H.
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2017, 112 (04): : 613 - 621
  • [50] TIME TO RESPONSE OF LINACLOTIDE IN TREATING FUNCTIONAL CONSTIPATION IN PEDIATRIC PATIENTS AGED 6-17 YEARS: DATA FROM A PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED TRIAL
    Nurko, Samuel
    Di Lorenzo, Carlo
    Huh, Susanna Y.
    Rodriguez-Araujo, Gerardo
    Ando, Masakazu
    Hyams, Jeffrey S.
    Khlevner, Julie
    Saps, Miguel
    GASTROENTEROLOGY, 2023, 164 (06) : S952 - S952
12345