Epidemiological study to evaluate the prevalence of BRAF V600 mutation in patients (pts) diagnosed with advanced melanoma (AM) in routine clinical practice in Spain.

被引:0
|
作者
Arance Fernandez, Ana Maria
Alos Hernandez, Lucia
Cerezuela Fuentes, Pablo
Ortiz Reina, Sebastian
Ortega Izquierdo, Eugenia
Marti Laborda, Rosa Ma
Soberino, Jesus
Ferrer Fabrega, Berta
Rubio, Jordi
Perez Bueno, Fernando
Teresa Perez-Hoyos, Maria
Cancho Galan, Goikoane
Ballesteros Garcia, Ana Isabel
Fraga Fernandez, Javier
Marquez Rodas, Ivan
Parra, Veronica
Montagut Viladot, Clara
Bellosillo, Beatriz
Luis Rodriguez-Peralto, Jose
Lopez-Martin, Jose A.
机构
[1] Hosp Clin Barcelona, Med Oncol, Barcelona, Spain
[2] Hosp Clin Barcelona, Barcelona, Spain
[3] Hosp Santa Maria del Rosell, Cartagena, Spain
[4] Hosp Arnau Vilanova, Lleida, Spain
[5] Univ Hosp Vall dHebron, Barcelona, Spain
[6] Hosp Vall de Hebron, Barcelona, Spain
[7] Hosp Josep Trueta, Girona, Spain
[8] Hosp Dr Josep Trueta, Girona, Spain
[9] Basurto Univ Hosp, Bilbao, Spain
[10] Hosp Univ Basurto, Bilbao, Spain
[11] Hosp Univ La Princesa, Madrid, Spain
[12] Hosp La Princesa, Madrid, Spain
[13] Hosp Gregorio Maranon, Madrid, Spain
[14] Hosp del Mar, Barcelona, Spain
[15] Hosp del Mar, Dept Pathol, Barcelona, Spain
[16] Hosp Doce Octubre, Pathol Anat Serv, Madrid, Spain
[17] Hosp 12 Octubre, E-28041 Madrid, Spain
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
e20115
引用
收藏
页数:1
相关论文
共 40 条
  • [31] Tumor microenvironment (TME), longitudinal biomarker changes, and clinical outcome in patients (pts) with advanced BRAF V600-mutant melanoma treated with first-line spartalizumab (S) plus dabrafenib (D) plus trametinib (T)
    Dummer, Reinhard
    Gusenleitner, Daniel
    Campbell, Catarina D.
    Lebbe, Celeste
    Atkinson, Victoria
    Mandala, Mario
    Nathan, Paul D.
    Arance, Ana
    Richtig, Erika
    Yamazaki, Naoya
    Robert, Caroline
    Schadendorf, Dirk
    Tawbi, Hussein Abdul-Hassan
    Ascierto, Paolo Antonio
    Ribas, Antoni
    Flaherty, Keith
    Gasal, Eduard
    Brase, Jan C.
    Long, Georgina V.
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (05)
  • [32] Tumor microenvironment (TME), longitudinal biomarker changes, and clinical outcome in patients (pts) with advanced BRAF V600-mutant melanoma treated with first-line spartalizumab (S) plus dabrafenib (D) plus trametinib (T).
    Dummer, Reinhard
    Gusenleitner, Daniel
    Campbell, Catarina D.
    Lebbe, Celeste
    Atkinson, Victoria
    Mandala, Mario
    Nathan, Paul D.
    Arance, Ana
    Richtig, Erika
    Yamazaki, Naoya
    Robert, Caroline
    Schadendorf, Dirk
    Tawbi, Hussein Abdul-Hassan
    Ascierto, Paolo Antonio
    Ribas, Antoni
    Flaherty, Keith
    Gasal, Eduard
    Brase, Jan C.
    Long, Georgina V.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [33] BeyPro1: a Phase II single-arm study for the treatment after recurrence of advanced melanoma patients harboring the V600BRAF mutation and pretreated with Vemurafenib, with the association of Vemurafenib plus Fotemustine
    Queirolo, P.
    Spagnolo, F.
    Picasso, V.
    Simeone, E.
    Grimaldi, A. M.
    Curvietto, M.
    Giorello, L.
    Fontana, V.
    Merlo, D. F.
    Ascierto, P. A.
    Bruzzi, P.
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S683 - S683
  • [34] BeyPro1: A phase II single-arm study for the treatment after recurrence of advanced melanoma patients harboring the V600BRAF mutation and pretreated with vemurafenib, with the association of vemurafenib plus fotemustine
    Queirolo, Paola
    Spagnolo, Francesco
    Picasso, Virginia
    Tornari, Elena
    Ottaviano, Vincenzo
    Glorello, Laura
    Simeone, Ester
    Grimaldi, Antonio Maria
    Curvietto, Marcello
    Mario, Domenico Franco
    Ascierto, Paolo Antonio
    Bruzzi, Paolo
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [35] A multi-center phase II study of high dose IL-2 (HD IL-2) sequenced with vemurafenib in patients with BRAF-V600E mutation positive advanced melanoma
    Clark, Joseph
    Ernstoff, Marc S.
    Milhem, Mohammed M.
    Lao, Christopher D.
    Lawson, David H.
    Flaherty, Lawrence E.
    Luna, Theresa L.
    Aung, Sandra
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [36] BREAK-MB: A phase II study assessing overall intracranial response rate (OIRR) to dabrafenib (GSK2118436) in patients (pts) with BRAF V600E/k mutation-positive melanoma with brain metastases (mets).
    Kirkwood, John M.
    Long, Georgina V.
    Trefzer, Uwe
    Davies, Michael A.
    Ascierto, Paolo Antonio
    Chapman, Paul B.
    Puzanov, Igor
    Hauschild, Axel
    Robert, Caroline
    Kefford, Richard
    Goodman, Vicki L.
    Switzky, Julie C.
    Swann, R. Suzanne
    Martin, Anne-Marie
    Guckert, Mary E.
    Streit, Michael R. W.
    Schadendorf, Dirk
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [37] LOGIC2: Phase 2, multi-center, open-label study of sequential encorafenib/binimetinib combination followed by a rational combination with targeted agents after progression, to overcome resistance in adult patients with locally-advanced or metastatic BRAF V600 melanoma
    Dummer, R.
    Sandhu, S.
    Hassel, J. C.
    Munoz, E.
    Berking, C.
    Gesierich, A.
    Ascierto, P. A.
    Esposito, O.
    Carter, K.
    Antona, V.
    Radhakrishnan, R.
    Cui, X.
    Caponigro, G.
    Jaeger, S.
    Demuth, T.
    Miller, W. H., Jr.
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S667 - S668
  • [38] Preliminary findings from part 1 of COMBI-i: A phase III study of anti-PD-1 antibody PDR001 combined with dabrafenib (D) and trametinib (T) in previously untreated patients (pts) with advanced BRAF V600-mutant melanoma.
    Dummer, Reinhard
    Fernandez, Ana Maria Arance
    Hansson, Johan
    Larkin, James M. G.
    Long, Georgina V.
    Gasal, Eduard
    Kaper, Mathilde
    Upalawanna, Allison
    Mookerjee, Bijoyesh
    Victoria
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (05)
  • [39] Overall survival in COMBI-d, a randomized, double-blinded, phase III study comparing the combination of dabrafenib and trametinib with dabrafenib and placebo as first-line therapy in patients (pts) with unresectable or metastatic BRAF V600E/K mutation-positive cutaneous melanoma
    Long, Georgina V.
    Stroyakovskiy, Daniil
    Gogas, Helen
    Levchenko, Evgeny
    De Braud, Filippo G.
    Larkin, James M. G.
    Garbe, Claus
    Jouary, Thomas
    Hauschild, Axel
    Grob, Jean Jacques
    Chiarion-Sileni, Vanna
    Lebbe, Celeste
    Mandala, Mario
    Millward, Michael
    DeMarini, Douglas James
    Irani, Jhangir G.
    Jin, Fan
    Swann, R. Suzanne
    Mookerjee, Bijoyesh
    Flaherty, Keith
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [40] Two year estimate of overall survival in COMBI-v, a randomized, open-label, phase III study comparing the combination of dabrafenib (D) and trametinib (T) with vemurafenib (Vem) as first-line therapy in patients (pts) with unresectable or metastatic BRAF V600E/K mutation-positive cutaneous melanoma
    Robert, C.
    Karaszewska, B.
    Schachter, J.
    Rutkowski, P.
    Mackiewicz, A.
    Stroyakovskiy, D.
    Lichinitser, M.
    Dummer, R.
    Grange, F.
    Mortier, L.
    Chiarion-Sileni, V.
    Drucis, K.
    Krajsova, I.
    Hauschild, A.
    Mookerjee, B.
    Legos, J.
    Schadendorf, D.
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S663 - S664