Green Conditions for Passerini Three-Component Synthesis of Tocopherol Analogues

被引：17
|
作者：
Ingold, Mariana [1 ]
Lopez, Gloria V. [1 ]
Porcal, Williams [1 ]
机构：
[1] Univ Republica, Fac Ciencias, Fac Quim, Grp Quim Med,Lab Quim Organ, Montevideo 11400, Uruguay
来源：
ACS SUSTAINABLE CHEMISTRY & ENGINEERING | 2014年 / 2卷 / 05期
关键词：
Geen chemistry; Passerini reaction; Water; Microwave; Tocopherol; MULTICOMPONENT REACTIONS; ORGANIC-SYNTHESIS; WATER;
D O I：
10.1021/sc5002116
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Passerini three-component reaction of a furoxan aldehyde, phenylethylisocyanide, and trolox derivatives under green conditions are reported. The Passerini reaction to obtain tocopherol mimetics can be efficiently carried out either solvent-free or in aqueous conditions under microwave irradiation, which are standards of green chemistry and characteristic of an ideal synthesis.
引用
收藏
页码：1093 / 1097
页数：5
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