Screening for undiagnosed parkinsonism in people aged 65 years and over in the community

被引：16

作者：

Taylor, KSM ^{[1
]}

Counsell, CE ^{[1
]}

Harris, CE ^{[1
]}

Gordon, JC ^{[1
]}

机构：

[1] Univ Aberdeen, Dept Med & Therapeut, Aberdeen AB25 2ZD, Scotland

来源：

PARKINSONISM & RELATED DISORDERS | 2006年 / 12卷 / 02期

关键词：

parkinsonism; screening; community; older adults; incidence;

D O I：

10.1016/j.parkreldis.2005.08.005

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We screened a random sample of 2449 people aged 65 years and over for undiagnosed parkinsonism, using a postal screening questionnaire followed by clinical neurological assessment. Amongst the 1556 (63.5%) patients who responded, four patients with previously undiagnosed parkinsonism were identified, suggesting a prevalence of 257 per 100,000 (95% CI 70, 658) in this age-group. Although only small, the numbers were sufficient to significantly increase the incidence of parkinsonism in an incidence study. Two simple screening questions achieved a high sensitivity for newly diagnosed parkinsonism of 95%, but a low specificity of 28%. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：79 / 85

页数：7

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