The lifespan determinant p66shc drives obesity-induced oxidative stress, mitochondrial dysfunction and vascular inflammation

被引：0
|
作者：
Paneni, F. [1 ]
Capretti, G. [2 ]
Costantino, S. [3 ]
Chiandotto, S. [2 ]
Akhmedov, A. [3 ]
Di Stasio, E. [4 ]
Rocca, B. [4 ]
Luscher, T. F. [3 ]
Volpe, M. [2 ]
Cosentino, F. [2 ]
机构：
[1] Univ Roma La Sapienza, St Andrea Hosp, I-00185 Rome, Italy
[2] Univ Roma La Sapienza, Dept Clin & Mol Med, I-00185 Rome, Italy
[3] Univ Zurich, Inst Physiol, Zurich, Switzerland
[4] Univ Cattolica Sacro Cuore, Dept Pharmacol, I-00168 Rome, Italy
来源：
EUROPEAN HEART JOURNAL | 2013年 / 34卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：159 / 159
页数：1
相关论文
共 50 条
  • [21] p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis
    Shin, Hyo Jung
    Park, Hyewon
    Shin, Nara
    Shin, Juhee
    Gwon, Do Hyeong
    Kwon, Hyeok Hee
    Yin, Yuhua
    Hwang, Jeong-Ah
    Hong, Jinpyo
    Heo, Jun Young
    Kim, Cuk-Seong
    Joo, Yongbum
    Kim, Youngmo
    Kim, Jinhyun
    Beom, Jaewon
    Kim, Dong Woon
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2020, 15 : 2379 - 2390
  • [22] Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders
    Lebiedzinska, Magdalena
    Karkucinska-Wieckowska, Agnieszka
    Giorgi, Carlotta
    Karczmarewicz, Elzbieta
    Pronicka, Ewa
    Pinton, Paolo
    Duszynski, Jerzy
    Pronicki, Maciej
    Wieckowski, Mariusz R.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2010, 1797 (6-7): : 952 - 960
  • [23] Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders
    Lebiedzinska, Magdalena
    Karkucinska-Wieckowska, Agnieszka
    Giorgi, Carlotta
    Karczmarewicz, Elzbieta
    Pronicka, Ewa
    Pinton, Paolo
    Duszynski, Jerzy
    Pronicki, Maciej
    Wieckowski, Mariusz R.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2010, 1797 : 57 - 57
  • [24] Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis
    Daojuan Wang
    Tingyu Wang
    Rong Wang
    Xinlin Zhang
    Lei Wang
    Zou Xiang
    Lingjia Zhuang
    Shanmei Shen
    Hongwei Wang
    Qian Gao
    Yong Wang
    Journal of Translational Medicine, 18
  • [25] Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis
    Wang, Daojuan
    Wang, Tingyu
    Wang, Rong
    Zhang, Xinlin
    Wang, Lei
    Xiang, Zou
    Zhuang, Lingjia
    Shen, Shanmei
    Wang, Hongwei
    Gao, Qian
    Wang, Yong
    JOURNAL OF TRANSLATIONAL MEDICINE, 2020, 18 (01)
  • [26] Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway
    Wojtala, Aleksandra
    Karkucinska-Wieckowska, Agnieszka
    Sardao, Vilma A.
    Szczepanowska, Joanna
    Kowalski, Pawel
    Pronicki, Maciej
    Duszynski, Jerzy
    Wieckowski, Mariusz R.
    MITOCHONDRION, 2017, 37 : 62 - 79
  • [27] Dynamic SIRTUIN1-modulated Lysine Acetylation of P66shc Governs Vascular Endothelial Oxidative Stress and Dysfunction of Diabetes
    Kumar, Santosh
    Kim, Young Rae
    Vikram, Ajit
    Naqvi, Asma
    Kumar, Ajay
    Bachschmid, Markus
    Jacobs, Julia S.
    Irani, Kaikobad
    CIRCULATION, 2014, 130
  • [28] Role of p66Shc in the Modulation of Oxidative Stress in Human Liver Cells
    De Stefano, Francesca
    Perrini, Sebastio
    Natalicchio, Annalisa
    Tortosa, Federica
    Peschechera, Alessandro
    Melchiorre, Mariangela
    Martemucci, Sabina
    Losurdo, Fabrizio
    Laviola, Luigi
    Giorgino, Francesco
    DIABETES, 2009, 58 : A388 - A388
  • [29] Role of p66Shc in the modulation of oxidative stress in human liver cells
    De Stefano, F.
    Perrini, S.
    Natalicchio, A.
    Tortosa, F.
    Peschechera, A.
    Melchiorre, M.
    Martemucci, S.
    Losurdo, F.
    Laviola, L.
    Giorgino, F.
    DIABETOLOGIA, 2009, 52 : S51 - S51
  • [30] p66Shc Drives Persistent Oxidative Stress and Inflammation in the Diabetic Heart: Insights for the Progression of Cardiovascular Complications Despite Intensive Glycemic Control
    Costantino, Sarah
    Paneni, Francesco
    Berrino, Liberato
    Volpe, Massimo
    Luscher, Thomas Felix
    Cosentino, Francesco
    CIRCULATION, 2012, 126 (21)
12345