Biocompatible Sodium Alginate Electrospun Nanofiber using Eriobotrya Japonica and Jasmine Sambac leaf extracts

Sodium Alginate (SA) has earned industrial recognition due to its biocompatibility, biodegradability and especially its watersoluble nature that attracts various important elements to produce electrospun nanofibers. The purpose of this study is to develop optimized uniform bead free biocompatible ecofriendly nanofibers from SA along with polyvinyl alcohol (PVA) (which serve as base material) incorporated with plant leaf extracts (water) of Eriobotrya Japonica (ER) and Jasmine Sambac (JS) through electrospinning with an average diameter of +/- 23 to +/- 272 nm. The extracts were manipulated at three concentrations ( 0.5, 1, and 1.5% w/v). Fourier transform infrared spectroscopy confirmed the presence of SA and plant extracts in nanofibers. X-Ray-diffraction results showed that nanofibers lose their crystallinity as the plant extract are loaded into SA/PVA8 nanofibers. Agar disc diffusion method was used to assess the antibacterial properties of nanofibers which showed that SAER nanofibers exhibited good to fair antibacterial properties against E. coli than S.aureus. The antioxidant capacities were checked through DPPH free radical scavenging assay which showed that SAER nanofibers have excellent antioxidant capacities and it continue to increase as the concentration of the plant extract increased in the SA/PVA8 nanofibers. The developed nanofibers showed excellent biocompatible promising material for biomedical textiles.