Characterization of the transport topology in patient-specific abdominal aortic aneurysm models

被引:70
|
作者
Arzani, Amirhossein [1 ]
Shadden, Shawn C. [1 ]
机构
[1] IIT, Dept Mech Mat & Aerosp Engn, Chicago, IL 60616 USA
基金
美国国家卫生研究院;
关键词
LAGRANGIAN COHERENT STRUCTURES; NAVIER-STOKES EQUATIONS; PULSATILE FLOW; BLOOD-FLOW; PROGRESSIVE ENLARGEMENT; INTRALUMINAL THROMBUS; FLUID-DYNAMICS; BIOMECHANICS; SIMULATION; STRESSES;
D O I
10.1063/1.4744984
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
Abdominal aortic aneurysm (AAA) is characterized by disturbed blood flow patterns that are hypothesized to contribute to disease progression. The transport topology in six patient-specific abdominal aortic aneurysms was studied. Velocity data were obtained by image-based computational fluid dynamics modeling, with magnetic resonance imaging providing the necessary simulation parameters. Finite-time Lyapunov exponent (FTLE) fields were computed from the velocity data, and used to identify Lagrangian coherent structures (LCS). The combination of FTLE fields and LCS was used to characterize topological flow features such as separation zones, vortex transport, mixing regions, and flow impingement. These measures offer a novel perspective into AAA flow. It was observed that all aneurysms exhibited coherent vortex formation at the proximal segment of the aneurysm. The evolution of the systolic vortex strongly influences the flow topology in the aneurysm. It was difficult to predict the vortex dynamics from the aneurysm morphology, motivating the application of image-based flow modeling. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4744984]
引用
收藏
页数:16
相关论文
共 50 条
  • [41] Efficient parallel simulation of hemodynamics in patient-specific abdominal aorta with aneurysm
    Qin, Shanlin
    Wu, Bokai
    Liu, Jia
    Shiu, Wen-Shin
    Yan, Zhengzheng
    Chen, Rongliang
    Cai, Xiao-Chuan
    COMPUTERS IN BIOLOGY AND MEDICINE, 2021, 136
  • [42] Influence of the flow field and vortex structure of patient-specific abdominal aortic aneurysm with intraluminal thrombus on the arterial wall
    Zhan, Jie-min
    Lu, Tian-dong
    Yang, Zhi-yun
    Hu, Wen-qing
    Su, Wei
    ENGINEERING APPLICATIONS OF COMPUTATIONAL FLUID MECHANICS, 2022, 16 (01) : 2100 - 2122
  • [43] Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft
    Molony, David S.
    Callanan, Anthony
    Kavanagh, Eamon G.
    Walsh, Michael T.
    McGloughlin, Tim M.
    BIOMEDICAL ENGINEERING ONLINE, 2009, 8 : 24
  • [44] Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft
    David S Molony
    Anthony Callanan
    Eamon G Kavanagh
    Michael T Walsh
    Tim M McGloughlin
    BioMedical Engineering OnLine, 8
  • [45] Patient-Specific Mechanical Characterization Of Abdominal Aortic Aneurysms Using 4D Ultrasound
    van Disseldorp, E. M. J.
    Petterson, N. J.
    Rutten, M. C. M.
    van de Vosse, F. N.
    van Sambeek, M. R. H. M.
    Lopata, R. G. P.
    ULTRASCHALL IN DER MEDIZIN, 2017, 38 (01): : 92 - 93
  • [46] Identification of in vivo material and geometric parameters of a human aorta: toward patient-specific modeling of abdominal aortic aneurysm
    Zeinali-Davarani, Shahrokh
    Raguin, L. Guy
    Vorp, David A.
    Baek, Seungik
    BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2011, 10 (05) : 689 - 699
  • [47] INNOVATIVE DESIGN AND MANUFACTURING TECHNIQUES FOR PATIENT SPECIFIC ABDOMINAL AORTIC ANEURYSM FLEXIBLE BENCHTOP MODELS
    Stefanov, Florian
    Delassus, Patrick
    McGloughlin, Tim
    Morris, Liam
    PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2013, PT A, 2014,
  • [48] Integrated particle image velocimetry and fluid–structure interaction analysis for patient-specific abdominal aortic aneurysm studies
    Can Özcan
    Özgür Kocatürk
    Civan Işlak
    Cengizhan Öztürk
    BioMedical Engineering OnLine, 22
  • [49] Identification of in vivo material and geometric parameters of a human aorta: toward patient-specific modeling of abdominal aortic aneurysm
    Shahrokh Zeinali-Davarani
    L. Guy Raguin
    David A. Vorp
    Seungik Baek
    Biomechanics and Modeling in Mechanobiology, 2011, 10 : 689 - 699
  • [50] Comparison of patient-specific inlet boundary conditions in the numerical modelling of blood flow in abdominal aortic aneurysm disease
    Hardman, David
    Semple, Scott I.
    Richards, Jennifer M. J.
    Hoskins, Peter R.
    INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 2013, 29 (02) : 165 - 178