Hydrolytically stable and selective P2Y1/6 receptor agonists

被引：0
|
作者：
Fischer, Bilha [1 ]
Eliahu, Shay E. [1 ]
Yelovitch, Shir [1 ]
Nahum, Vicky [1 ]
Camden, Jean [2 ]
Weisman, Gary [2 ]
Lecka, Joanna [3 ]
Sevigny, Jean [3 ]
Reiser, Georg [4 ]
机构：
[1] Bar Ilan Univ, Dept Chem, IL-52900 Ramat Gan, Israel
[2] Univ Missouri, Bond Life Sci Ctr 540E, Dept Biochem, Columbia, MO 65211 USA
[3] Univ Laval, Ctr Hosp Univ Quebec, Ctr Rech Rhumatol & Immunol, Quebec City, PQ, Canada
[4] Otto Von Guericke Univ, Fak Med, Inst Neurobiochem, D-39120 Magdeburg, Germany
来源：
PURINERGIC SIGNALLING | 2008年 / 4卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：S18 / S18
页数：1
相关论文
共 50 条
  • [31] P2Y1 receptor antagonists as novel antithrombotic agents
    Pfefferkorn, Jeffrey A.
    Choi, Chulho
    Winters, Thomas
    Kennedy, Robert
    Chi, Liguo
    Perrin, Lisa A.
    Lu, Gina
    Ping, Yun-Wen
    McClanahan, Tom
    Schroeder, Richard
    Leininger, Michael T.
    Geyer, Andrew
    Schefzick, Sabine
    Atherton, James
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (11) : 3338 - 3343
  • [32] Homologous desensitization of the platelet P2Y1 receptor.
    Quinton, TM
    Kunapuli, SP
    BLOOD, 1999, 94 (10) : 67B - 67B
  • [33] Identification of Contractile P2Y1, P2Y6, and P2Y12 Receptors in Rat Intrapulmonary Artery Using Selective Ligands
    Mitchell, Callum
    Syed, Nawazish-i-Husain
    Tengah, Asrin
    Gurney, Alison M.
    Kennedy, Charles
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2012, 343 (03): : 755 - 762
  • [34] Synthetic studies for difluoromethylenephosphonate analogues of MRS2216, a selective P2Y1 receptor antagonist
    Hikishima, Sadao
    Takatori, Arihiro
    Kojima, Atsushi
    Yokomatsu, Tsutomu
    DRUGS OF THE FUTURE, 2007, 32 : 48 - 48
  • [35] Pharmacodynamic interplay of the P2Y1, P2Y12, and TxA2 pathways in platelets: The potential of triple antiplatelet therapy with P2Y1 receptor antagonism
    Oestreich, Julie H.
    Ferraris, Suellen P.
    Steinhubl, Steven R.
    Akers, Wendell S.
    THROMBOSIS RESEARCH, 2013, 131 (02) : E64 - E70
  • [36] P2Y1, P2Y2, P2Y6, and P2Y12 nucleotide receptor subtypes expression during C6 glioma cell differentiation
    Garcia-Colon, JO
    Cruz, A
    Rubio, M
    Aquino, EE
    Miranda, JD
    Gonzalez, FA
    Silva, WI
    FASEB JOURNAL, 2006, 20 (05): : A1286 - A1286
  • [37] Molecular modeling and dynamics studies of the synthetic small molecule agonists with GPR17 and P2Y1 receptor
    Murugesan, Akshaya
    Nguyen, Phung
    Ramesh, Thiyagarajan
    Yli-Harja, Olli
    Kandhavelu, Meenakshisundaram
    Saravanan, Konda Mani
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2022, 40 (23): : 12908 - 12916
  • [38] Adenine nucleotide analogues locked in a northern methanocarba conformation:: Enhanced stability and potency as P2Y1 receptor agonists
    Ravi, RG
    Kim, HS
    Servos, J
    Zimmermann, H
    Lee, K
    Maddileti, S
    Boyer, JL
    Harden, TK
    Jacobson, KA
    JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (10) : 2090 - 2100
  • [39] The role of P2Y1 receptor signaling in central respiratory control
    Rajani, V.
    Zhang, Y.
    Revill, A. L.
    Funk, G. D.
    RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 2016, 226 : 3 - 10
  • [40] Regulation of P2Y1 receptors
    Glast, Dionne
    Houston, Dayle
    Qi, Ai-Dong
    Harden, T. Kendall
    Nicholas, Robert A.
    PURINERGIC SIGNALLING, 2008, 4 : S79 - S79
12345