Dopamine Is Differentially Encoded by D2 Receptors in Striatal Subregions

被引:3
|
作者
Engeln, Michel [1 ]
Fox, Megan E. [1 ]
Lobo, Mary Kay [1 ]
机构
[1] Univ Maryland, Sch Med, Dept Anat & Neurobiol, Baltimore, MD 21201 USA
关键词
D O I
10.1016/j.neuron.2018.04.016
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Striatal dopamine signaling is differentially regulated along the dorso-ventral axis, but how these differences are encoded by dopamine receptors is unknown. In this issue of Neuron, Marcott et al. (2018) show that dopamine activates D2 receptors in regionally distinct ways and dissect the underlying mechanisms behind striatal D2 heterogeneity.
引用
收藏
页码:459 / 461
页数:3
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