Slow-Release Behaviors of Poly(vinyl alcohol)/Poly(N, N-diethylacrylamide-co-methacrylic acid) Semi-IPN Materials

A series of semi-interpenetrating polymer materials of poly(vinyl alcohol)/poly(N, N-diethylacrylamide-co-methacrylic acid)(PVA/PDM) were synthesized by free radical copolymerization techniques and semi-interpenetrating polymer network techniques at room temperature with ammonium persulfate and N,N,N',N'-tetramethylethylene diamide as initiators and N,N'-methylenebisacrylamide as a crosslinker. The interior morphology by scanning electron microscopy (SEM) revealed that PVA introduced PDM materials have interconnected porous network structures. The release behaviors of the model drug, aminophylline, are found dependent on material composition and environmental temperature, which suggests that these materials have potential application as intelligent release carriers.